Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.68 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.68 |
| ▸ | MEN1 | O00255 | 1/20 | 0.68 |
| ▸ | MAPT | P10636 | 1/20 | 0.68 |
| ▸ | THRB | P10828 | 1/20 | 0.68 |
| ▸ | HPGD | P15428 | 1/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.68 |
| ▸ | PNP | P00491 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.40 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.36 |
| ▸ | FGFR2 | P21802 | 2/20 | 0.36 |
| ▸ | NOS1 | P29475 | 2/20 | 0.34 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Xanthopterin SCHEMBL906219 | 0.82 | KDM4E (1.00) | KDM4EALDH1A1HSD17B10MEN1MAPT | |
| Xanthopterin SCHEMBL6475881 | 0.81 | KDM4E (0.96) | KDM4EALDH1A1HSD17B10MEN1MAPT | |
| SCHEMBL7626 | 0.69 | EGFR (0.34) | — | |
| SCHEMBL29355369 | 0.69 | EGFR (0.34) | — | |
| SCHEMBL13833239 | 0.69 | KDM4E (0.49) | KDM4EALDH1A1HSD17B10MEN1MAPT | |
| Guanine SCHEMBL1100665 | 0.68 | PNP (0.70) | KDM4EALDH1A1HSD17B10MEN1MAPT | |
| Formaldehyde SCHEMBL28263973 | 0.67 | EGFR (0.31) | — | |
| Phosphine SCHEMBL3090397 | 0.67 | CHRNB4 (0.33) | — | |
| Hydrogen Sulfide SCHEMBL29184284 | 0.67 | EGFR (0.33) | — | |
| Ammonia Solution, Strong SCHEMBL27506828 | 0.67 | EGFR (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9207205-B2 | Method and apparatus for cancer screening | THE CURATORS OF THE UNIVERSITY OF MISSOURI (US) | 2015-12-08 | — | — | US | disclosed |
| US-20110147217-A1 | METHOD AND APPARATUS FOR CANCER SCREENING | THE CURATORS OF THE UNIVERSITY OF MISSOURI (US) | 2011-06-23 | — | — | US | disclosed |