Xanthopterin

Xanthopterin

SCHEMBL906219

Nc1nc2ncc(=O)[nH]c2c(=O)[nH]1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 2/20 1.00
▸ ALDH1A1 P00352 2/20 1.00
▸ HSD17B10 Q99714 2/20 1.00
▸ MEN1 O00255 1/20 1.00
▸ MAPT P10636 1/20 1.00
▸ THRB P10828 1/20 1.00
▸ HPGD P15428 1/20 1.00
▸ KMT2A Q03164 1/20 1.00
▸ PNP P00491 5/20 0.62
▸ LMNA P02545 1/20 0.54
▸ GLA P06280 1/20 0.54
▸ PMP22 Q01453 1/20 0.54
▸ FGFR1 P11362 2/20 0.49
▸ FGFR2 P21802 2/20 0.49
▸ NOS1 P29475 3/20 0.45
▸ AKR1B1 P15121 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Xanthopterin SCHEMBL6475881 0.98 KDM4E (0.96) KDM4EALDH1A1HSD17B10MEN1MAPT
Xanthopterin SCHEMBL1979618 0.82 KDM4E (0.68) KDM4EALDH1A1HSD17B10MEN1MAPT
8-Aminoguanine SCHEMBL21761 0.78 PNP (1.00) KDM4EALDH1A1HSD17B10MEN1MAPT
Guanine SCHEMBL986801 0.76 PNP (1.00) KDM4EALDH1A1HSD17B10MEN1MAPT
Guanine SCHEMBL1264884 0.76 PNP (1.00) KDM4EALDH1A1HSD17B10MEN1MAPT
Guanine SCHEMBL5260 0.76 PNP (1.00) KDM4EALDH1A1HSD17B10MEN1MAPT
Guanine SCHEMBL2895089 0.74 PNP (0.96) KDM4EALDH1A1HSD17B10MEN1MAPT
Guanine SCHEMBL19436607 0.74 PNP (0.96) KDM4EALDH1A1HSD17B10MEN1MAPT
Guanine SCHEMBL22533907 0.74 PNP (0.96) KDM4EALDH1A1HSD17B10MEN1MAPT
Guanine SCHEMBL21611718 0.74 PNP (0.96) KDM4EALDH1A1HSD17B10MEN1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 237 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12473287-B2 Synthetic co-crystals of anhydrous guanine and process for preparing the same ECOCRYSTAL LTD. (IL) 2025-11-18 — — US claimed
US-20240208977-A1 SYNTHETIC CO-CRYSTALS OF ANHYDROUS GUANINE AND PROCESS FOR PREPARING THE SAME ECOCRYSTAL LTD. (IL) 2024-06-27 — — US claimed
US-11858936-B2 Synthetic co-crystals of anhydrous guanine and process for preparing the same GUR, Dvir (IL) 2024-01-02 — — US claimed
US-11415583-B2 Method, kit, and apparatus for cancer detection using urinary tumor markers NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY (JP) 2022-08-16 — — US claimed
US-20220098199-A1 SYNTHETIC CO-CRYSTALS OF ANHYDROUS GUANINE AND PROCESS FOR PREPARING THE SAME GUR, Dvir (IL) 2022-03-31 — — US claimed
US-20200150124-A1 METHOD, KIT, AND APPARATUS FOR CANCER DETECTION USING URINARY TUMOR MARKERS NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY 2020-05-14 — — US claimed
EP-3650862-A2 METHOD, KIT, AND APPARATUS FOR CANCER DETECTION USING URINARY TUMOR MARKERS National University Corporation Nagoya University (JP) 2020-05-13 — — EP claimed
CN-110787158-A Application of D609 in preparing medicine for preventing and treating retina injury diseases 中山大学中山眼科中心 2020-02-14 — — CN claimed
US-20190293653-A1 URINE METABOLITE MARKER FOR CHILDHOOD CANCER HITACHI, LTD. (JP) 2019-09-26 — — US claimed
WO-2019175332-A1 BH4 PATHWAY INHIBITION AND USE THEREOF FOR TREATING T-CELL MEDIATED AUTOIMMUNE DISEASES OR HYPERSENSITIVITY IMBA - INSTITUT FÜR MOLEKULARE BIOTECHNOLOGIE GMBH (AT) 2019-09-19 — — WO claimed
EP-1121111-A2 COMPOUNDS FOR THE TREATMENT OF WEIGHT LOSS IMPERIAL COLLEGE INNOVATIONS LIMITED (GB) 2001-08-08 — — EP claimed
EP-0673783-B1 Recording sheets containing purine, pyrimidine, benzimidazole, imidazolidine, urazole, pyrazole, triazole, benzotriazole, tetrazole, and pyrazine compounds XEROX CORP (US) 2000-07-05 — — EP claimed
WO-2000023448-A1 NOVEL PTERIN ANTINEOPLASTIC AGENTS MOHENO PHILLIP B B (US) 2000-04-27 — — WO claimed
WO-2000021509-A2 METHODS OF TREATMENT IMPERIAL COLLEGE INNOVATIONS LIMITED (GB) 2000-04-20 — — WO claimed
US-5659348-A APPLYING TO A SUBSTRATE XEROX CORPORATION (US) 1997-08-19 — — US claimed
US-5534514-A ANTITUMOR AGENTS OR FOR TREATMENT OF LEUKEMIA USING MIXTURES OF XANTHOPTERIN AND ISOXANTHOPTERIN SUSPENSION OF CARRIER SAN DIEGO STATE UNIVERSITY (US) 1996-07-09 — — US claimed
EP-0673783-A2 Recording sheets containing purine, pyrimidine, benzimidazole, imidazolidine, urazole, pyrazole, triazole, benzotriazole, tetrazole, and pyrazine compounds XEROX CORPORATION (US) 1995-09-27 — — EP claimed
EP-0170414-B1 PROCESS FOR TREATING METAL SURFACE Hitachi Chemical Co., Ltd. (JP) 1991-04-17 — — EP claimed
US-4643793-A WITH MIXTURE OF COPPER COMPOUND, COMPLEXING AGENT, REDUCING AGENT, AND PH ADJUSTER IN PRESENCE OF NITROGEN HETEROCYCLE COMPOUND HITACHI CHEMICAL COMPANY, LTD. (JP) 1987-02-17 — — US claimed
EP-0170414-A2 Process for treating metal surface Hitachi Chemical Co., Ltd. (JP) 1986-02-05 — — EP claimed
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