Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA5 | P22460 | 7/20 | 0.46 |
| ▸ | KCNN4 | O15554 | 5/20 | 0.46 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.43 |
| ▸ | USP8 | P40818 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28506438 | 0.90 | KCNA5 (0.46) | KCNA5KCNN4CYP11B1CYP11B2GAA | |
| SCHEMBL26023315 | 0.89 | KCNA5 (0.55) | KCNA5KCNN4CYP11B1CYP11B2GAA | |
| SCHEMBL14354081 | 0.89 | KCNA5 (0.55) | KCNA5KCNN4CYP11B1CYP11B2GAA | |
| SCHEMBL6568180 | 0.83 | ALDH1A1 (0.52) | GAALMNAMEN1KMT2AMAPT | |
| SCHEMBL2678331 | 0.83 | ALDH1A1 (0.52) | GAALMNAMEN1KMT2AMAPT | |
| SCHEMBL14353950 | 0.83 | KCNA5 (0.50) | KCNA5KCNN4GAACYP19A1ALDH1A1 | |
| SCHEMBL11868638 | 0.81 | ALDH1A1 (0.50) | GAALMNAMEN1KMT2AMAPT | |
| SCHEMBL21275949 | 0.81 | RAB9A (0.49) | KCNA5KCNN4GAACYP19A1LMNA | |
| SCHEMBL17614689 | 0.80 | KCNA5 (0.55) | KCNA5KCNN4GAALMNAMAPT | |
| SCHEMBL21309077 | 0.79 | ALDH1A1 (0.61) | GAALMNAMEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180026206-A1 | HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME | SAMSUNG DISPLAY CO., LTD. (KR) | 2018-01-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180026206-A1 | HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME | CRY1, CYP1A1, CYP1B1 | KCNA5 1497/4885KCNN4 2854/4885CYP11B1 140/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.