SCHEMBL2678331

SCHEMBL2678331

O=P(c1ccccc1)(c1ccc(Br)cc1)c1ccc(Br)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.52
MAPK1 P28482 1/20 0.52
LMNA P02545 2/20 0.50
TDP1 Q9NUW8 1/20 0.48
GAA P10253 1/20 0.45
CA2 P00918 1/20 0.44
CA4 P22748 1/20 0.44
CA5A P35218 1/20 0.44
MAOA P21397 2/20 0.43
MAOB P27338 2/20 0.43
MEN1 O00255 4/20 0.43
KMT2A Q03164 4/20 0.43
HPGD P15428 1/20 0.42
HTT P42858 1/20 0.42
ESR1 P03372 1/20 0.41
CYP2A6 P11509 1/20 0.40
CFTR P13569 1/20 0.39
MAPT P10636 1/20 0.39
NPC1 O15118 1/20 0.38
RAB9A P51151 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6568180 1.00 ALDH1A1 (0.52) ALDH1A1MAPK1LMNATDP1GAA
SCHEMBL11868638 0.98 ALDH1A1 (0.50) ALDH1A1MAPK1LMNATDP1GAA
SCHEMBL21309077 0.95 ALDH1A1 (0.61) ALDH1A1MAPK1LMNATDP1GAA
SCHEMBL23279569 0.89 ALDH1A1 (0.52) ALDH1A1MAPK1LMNATDP1GAA
SCHEMBL4258684 0.89 CYP2A6 (0.50) ALDH1A1MAPK1LMNATDP1CA2
SCHEMBL132983 0.87 LMNA (0.60) ALDH1A1LMNATDP1GAACA2
SCHEMBL5439069 0.87 LMNA (0.60) ALDH1A1LMNATDP1GAACA2
SCHEMBL5436616 0.87 LMNA (0.60) ALDH1A1LMNATDP1GAACA2
SCHEMBL14339307 0.84 ALDH1A1 (0.50) ALDH1A1MAPK1GAACA2MEN1
Triphenylphosphine Oxide SCHEMBL513223 0.84 CA2 (0.58) ALDH1A1LMNATDP1GAACA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 80 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115135698-B Process for producing cyclic polysiloxane 信越化学工业株式会社 2024-04-26 CN claimed
CN-112266467-A Polymer type phosphorus-nitrogen-containing flame retardant and preparation method thereof 欧阳杰 2021-01-26 CN claimed
CN-112210131-A Flame-retardant rubber and preparation method thereof 马海社 2021-01-12 CN claimed
EP-4108706-B1 METHOD FOR PRODUCING CYCLIC POLYSILOXANE SHINETSU CHEMICAL CO (JP) 2025-09-10 EP disclosed
CN-119968094-A Hole transport composition, hole transport layer, preparation method of hole transport layer and perovskite battery 天合光能股份有限公司 2025-05-09 CN disclosed
EP-3055891-B1 SEMICONDUCTING MATERIAL COMPRISING A PHOSPHINE OXIDE MATRIX AND METAL SALT NOVALED GMBH (DE) 2024-10-30 EP disclosed
CN-113563379-B Semiconductor material comprising a phosphine oxide matrix and a metal salt 诺瓦尔德股份有限公司 2024-05-24 CN disclosed
CN-115135698-B Process for producing cyclic polysiloxane 信越化学工业株式会社 2024-04-26 CN disclosed
EP-3281238-B1 SEMICONDUCTING MATERIAL COMPRISING A PHOSPHINE OXIDE MATRIX AND METAL SALT NOVALED GMBH (DE) 2024-04-24 EP disclosed
EP-3259786-B1 SEMICONDUCTING MATERIAL AND NAPHTOFURANE MATRIX COMPOUND FOR IT NOVALED GMBH (DE) 2023-08-30 EP disclosed
EP-3259786-B1 SEMICONDUCTING MATERIAL AND NAPHTOFURANE MATRIX COMPOUND FOR IT NOVALED GMBH (DE) 2023-08-30 EP disclosed
US-20070238856-A1 Trifluorovinyloxy monomers and polymers GENERAL ELECTRIC COMPANY 2007-10-11 US disclosed
US-20070080343-A1 New materials for electroluminescence and the utilization thereof MERCK PATENT GMBH (DE) 2007-04-12 US disclosed
US-20070080343-A1 New materials for electroluminescence and the utilization thereof MERCK PATENT GMBH (DE) 2007-04-12 US disclosed
US-20070080343-A1 New materials for electroluminescence and the utilization thereof MERCK PATENT GMBH (DE) 2007-04-12 US disclosed
EP-1250341-B1 A METHOD OF GENERATING A FUNCTIONALISED ARYLPHOSPHINE UNIV LIVERPOOL (GB) 2004-03-31 EP disclosed
US-20040059159-A2 A Method of Generating A Functionalised Arylphosphine THE UNIVERSITY OF LIVERPOOL (GB) 2004-03-25 US disclosed
US-20030181767-A1 Method of generating a functionalised arylphosphine XIAO JIANLIANG (GB) 2003-09-25 US disclosed
EP-1250341-A1 A METHOD OF GENERATING A FUNCTIONALISED ARYLPHOSPHINE THE UNIVERSITY OF LIVERPOOL (GB) 2002-10-23 EP disclosed
WO-2001055156-A1 A METHOD OF GENERATING A FUNCTIONALISED ARYLPHOSPHINE THE UNIVERSITY OF LIVERPOOL (GB) 2001-08-02 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030181767-A1 Method of generating a functionalised arylphosphine PHOSPHO1, PPIP5K2, PNPO ALDH1A1 2565/4885MAPK1 924/4885LMNA 4290/4885
US-20040059159-A2 A Method of Generating A Functionalised Arylphosphine PHOSPHO1, PFAS, PPIP5K2 ALDH1A1 2971/4885MAPK1 1233/4885LMNA 3548/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.