Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 2/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.41 |
| ▸ | MAOA | P21397 | 2/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | AHR | P35869 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.32 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21842178 | 0.80 | ALOX5 (0.44) | CHRM3ALOX5MAOAMAOBATM | |
| SCHEMBL7970207 | 0.80 | ALOX5 (0.44) | CHRM3ALOX5MAOAMAOBATM | |
| SCHEMBL1461770 | 0.80 | ALOX5 (0.44) | CHRM3ALOX5MAOAMAOBATM | |
| SCHEMBL28586543 | 0.76 | ALOX5 (0.41) | CHRM3ALOX5MAOAMAOBATM | |
| SCHEMBL13672457 | 0.76 | CHRM3 (0.45) | CHRM3ALOX5MAOAMAOBAHR | |
| SCHEMBL6129309 | 0.76 | CHRM3 (0.41) | CHRM3ALOX5MAOAMAOBATM | |
| SCHEMBL18535897 | 0.76 | CHRM3 (0.41) | CHRM3ALOX5MAOAMAOBATM | |
| SCHEMBL3289558 | 0.74 | ALOX5 (0.48) | CHRM3ALOX5MAOAMAOBATM | |
| SCHEMBL896505 | 0.73 | PNMT (0.39) | CHRM3ALOX5MAOAMAOBAHR | |
| SCHEMBL29722 | 0.73 | CHRM3 (0.46) | CHRM3ALOX5MAOAMAOBAHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160354533-A1 | ADSORBING PATHOGEN-INACTIVATING COMPOUNDS WITH POROUS PARTICLES IMMOBILIZED IN A MATRIX | CERUS CORPORATION (US) | 2016-12-08 | — | — | US | disclosed |
| US-9259525-B2 | Adsorbing pathogen-inactivating compounds with porous particles immobilized in a matrix | CERUS CORPORATION (US) | 2016-02-16 | — | — | US | disclosed |
| EP-2358814-B1 | PLASTICIZER FOR THERMOPLASTIC POLYMER MATERIALS | AVENT INC (US) | 2015-07-29 | — | — | EP | disclosed |
| EP-1508345-B1 | System and method for the reduction of small organic compounds from blood products | CERUS CORP (US) | 2013-09-25 | — | — | EP | disclosed |
| US-8518315-B2 | Plasticizer for thermoplastic materials | KIMBERLY-CLARK WORLDWIDE, INC. (US) | 2013-08-27 | — | — | US | disclosed |
| EP-2358814-A2 | PLASTICIZER FOR THERMOPLASTIC POLYMER MATERIALS | Kimberly-Clark Worldwide, Inc. (US) | 2011-08-24 | — | — | EP | disclosed |
| US-20110143621-A1 | PLASTICIZER FOR THERMOPLASTIC POLYMER MATERIALS | AVANOS MEDICAL SALES, LLC | 2011-06-16 | — | — | US | disclosed |
| US-7759302-B2 | Octapeptides: Arg-X-Asp-Leu-Asp-Ser-Leu-Arg where X is a 2-aminoaulfonylaminoalkanoic acid and optionally having various end groups; biologically active as ligands of blood platelet integrin GPIIbIIIa and the alpha v integrins | MERCK PATENT GMBH (DE) | 2010-07-20 | — | — | US | disclosed |
| US-20100160484-A1 | XANTHENE-BASED PLASTICIZER OF RESINS AND POLYMERS | AVANOS MEDICAL SALES, LLC | 2010-06-24 | — | — | US | disclosed |
| US-20100159769-A1 | PLASTICIZER FOR THERMOPLASTIC MATERIALS | AVANOS MEDICAL SALES, LLC | 2010-06-24 | — | — | US | disclosed |
| EP-1044066-A1 | BATCH DEVICES FOR THE REDUCTION OF COMPOUNDS FROM BIOLOGICAL COMPOSITIONS CONTAINING CELLS AND METHODS OF USE | Cerus Corporation (US) | 2000-10-18 | — | — | EP | disclosed |
| CN-1248178-A | Method and device for reducing small organic molecules in blood products | CERUS CORP (US) | 2000-03-22 | — | — | CN | disclosed |
| EP-0954374-A1 | METHODS AND DEVICES FOR THE REDUCTION OF SMALL ORGANIC COMPOUNDS FROM BLOOD PRODUCTS | Cerus Corporation (US) | 1999-11-10 | — | — | EP | disclosed |
| WO-1999034914-A1 | BATCH DEVICES FOR THE REDUCTION OF COMPOUNDS FROM BIOLOGICAL COMPOSITIONS CONTAINING CELLS AND METHODS OF USE | CERUS CORPORATION (US) | 1999-07-15 | — | — | WO | disclosed |
| WO-1999034915-A1 | FLOW DEVICES FOR THE REDUCTION OF COMPOUNDS FROM BIOLOGICAL COMPOSITIONS AND METHODS OF USE | CERUS CORPORATION (US) | 1999-07-15 | — | — | WO | disclosed |
| WO-1998030327-A1 | METHODS AND DEVICES FOR THE REDUCTION OF SMALL ORGANIC COMPOUNDS FROM BLOOD PRODUCTS | CERUS CORPORATION (US) | 1998-07-16 | — | — | WO | disclosed |
| EP-0471794-B1 | ANTIVIRAL THERAPY USING THIAZINE AND XANTHENE DYES | OKLAHOMA MED RES FOUND (US) | 1996-10-02 | — | — | EP | disclosed |
| EP-0471794-A4 | ANTIVIRAL THERAPY USING THIAZINE AND XANTHENE DYES | — | 1992-05-06 | — | — | EP | disclosed |
| EP-0471794-A1 | ANTIVIRAL THERAPY USING THIAZINE AND XANTHENE DYES. | OKLAHOMA MED RES FOUND (US) | 1992-02-26 | — | — | EP | disclosed |
| WO-1990013296-A1 | ANTIVIRAL THERAPY USING THIAZINE AND XANTHENE DYES | OKLAHOMA MEDICAL RESEARCH FOUNDATION (US) | 1990-11-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100160484-A1 | XANTHENE-BASED PLASTICIZER OF RESINS AND POLYMERS | SMARCA2, SMARCA1, MYB | CHRM3 724/4885ALOX5 805/4885MAOA 1730/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.