Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.48 |
| ▸ | MAOA | P21397 | 2/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | AHR | P35869 | 4/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.35 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.35 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.35 |
| ▸ | ITGAL | P20701 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29367681 | 0.90 | KDM4E (0.43) | ALOX5MAOAMAOBAHRCHRM3 | |
| SCHEMBL29403370 | 0.90 | KDM4E (0.43) | ALOX5MAOAMAOBAHRCHRM3 | |
| SCHEMBL5998195 | 0.90 | KDM4E (0.43) | ALOX5MAOAMAOBAHRCHRM3 | |
| SCHEMBL24140666 | 0.88 | ALOX5 (0.39) | ALOX5MAOAMAOBAHRCHRM3 | |
| Hydrochloric Acid SCHEMBL30913035 | 0.88 | KDM4E (0.42) | ALOX5MAOAMAOBAHRCHRM3 | |
| SCHEMBL19530889 | 0.88 | KDM4E (0.42) | ALOX5MAOAMAOBAHRCHRM3 | |
| SCHEMBL15030650 | 0.86 | ALOX5 (0.60) | ALOX5MAPK1GAANPSR1 | |
| SCHEMBL29373270 | 0.86 | ALOX5 (0.60) | ALOX5MAPK1GAANPSR1 | |
| SCHEMBL4388225 | 0.85 | ALOX5 (0.41) | ALOX5MAOAMAOBAHRCHRM3 | |
| SCHEMBL14278905 | 0.84 | MAOA (0.37) | ALOX5MAOAMAOBAHRCHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230192665-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORPORATION (US) | 2023-06-22 | — | — | US | disclosed |
| US-20210408398-A1 | HOLE TRANSPORT MATERIAL, PREPARATION METHOD THEREOF, AND ORGANIC LIGHT-EMITTING DEVICE | Wuhan China Star Optoelectronics Semiconductor Display Technology Co., Ltd (CN) | 2021-12-30 | — | — | US | disclosed |
| US-11038137-B2 | Organic electroluminescent materials and devices | UNIVERSAL DISPLAY CORPORATION (US) | 2021-06-15 | — | — | US | disclosed |
| US-10790455-B2 | Organic electroluminescent materials and devices | UNIVERSAL DISPLAY CORPORATION (US) | 2020-09-29 | — | — | US | disclosed |
| US-20180309067-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORPORATION | 2018-10-25 | — | — | US | disclosed |
| US-9929354-B2 | 9,9′-spirobixanthene derivatives for electroluminescent devices | MERCK PATENT GMBH (DE) | 2018-03-27 | — | — | US | disclosed |
| US-9929354-B2 | 9,9′-spirobixanthene derivatives for electroluminescent devices | MERCK PATENT GMBH (DE) | 2018-03-27 | — | — | US | disclosed |
| US-9929354-B2 | 9,9′-spirobixanthene derivatives for electroluminescent devices | MERCK PATENT GMBH (DE) | 2018-03-27 | — | — | US | disclosed |
| US-20160329507-A1 | 9,9'-SPIROBIXANTHENE DERIVATIVES FOR ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2016-11-10 | — | — | US | disclosed |
| US-9425401-B2 | 9,9′-spirobixanthene derivatives for electroluminescent devices | MERCK PATENT GMBH (DE) | 2016-08-23 | — | — | US | disclosed |
| US-20120211082-A1 | PHOTOELECTRIC CONVERSION DEVICE AND SOLAR CELL USING THE SAME | MITSUBISHI CHEMICAL CORPORATION (JP) | 2012-08-23 | — | — | US | disclosed |
| US-20120211082-A1 | PHOTOELECTRIC CONVERSION DEVICE AND SOLAR CELL USING THE SAME | MITSUBISHI CHEMICAL CORPORATION (JP) | 2012-08-23 | — | — | US | disclosed |
| EP-2463929-A1 | PHOTOELECTRIC CONVERSION ELEMENT AND SOLAR CELL USING SAME | Mitsubishi Chemical Corporation (JP) | 2012-06-13 | — | — | EP | disclosed |
| US-20110227054-A1 | OLED INCLUDING HOLE-CONDUCTING MATERIAL | KONINKLIJKE PHILIPS ELECTRONICS N.V. (NL) | 2011-09-22 | — | — | US | disclosed |
| US-7714149-B2 | Chiral spiro compounds and their use in asymmetric catalytic reactions | THE PENN STATE RESEARCH FOUNDATION (US) | 2010-05-11 | — | — | US | disclosed |
| US-7589218-B2 | Chiral spiro compounds and their use in asymmetric catalytic reactions | THE PENN STATE RESEARCH FOUNDATION (US) | 2009-09-15 | — | — | US | disclosed |
| US-20080293953-A1 | Chiral spiro compounds and their use in asymmetric catalytic reactions | THE PENN STATE RESEARCH FOUNDATION (US) | 2008-11-27 | — | — | US | disclosed |
| WO-2006028977-A2 | CHIRAL SPIRO COMPOUNDS AND THEIR USE IN ASYMMETRIC CATALYTIC REACTIONS | THE PENN STATE RESEARCH FOUNDATION (US) | 2006-03-16 | — | — | WO | disclosed |
| US-20060047128-A1 | (R)-O,O'-(9,9'-Spirobixanthene-1,1'-diyl)-N,N-Dimethylphosphoramide [(R)-4] ligand forms hydrogenation catalyst with Rh compounds for asymmetrical hydrogenation of olefins, imines, enamides and ketones | THE PENN STATE RESEARCH FOUNDATION | 2006-03-02 | — | — | US | disclosed |
| US-5763636-A | CONJUGATED POLYCYCLIC POLYMERS | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-06-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160329507-A1 | 9,9'-SPIROBIXANTHENE DERIVATIVES FOR ELECTROLUMINESCENT DEVICES | KCNK9, SLC9B2, SCN9A | ALOX5 2797/4885MAOA 1654/4885MAOB 594/4885 |
| US-20080293953-A1 | Chiral spiro compounds and their use in asymmetric catalytic reactions | NCOR2, NCOR1, NCOA2 | ALOX5 894/4885MAOA 1009/4885MAOB 802/4885 |
| US-20060047128-A1 | (R)-O,O'-(9,9'-Spirobixanthene-1,1'-diyl)-N,N-Dimethylphosphoramide [(R)-4] ligand forms hydrogenation catalyst with Rh compounds for asymmetrical hydrogenation of olefins, imines, enamides and ketones | NCOR2, NR3C2, NR4A2 | ALOX5 1068/4885MAOA 1626/4885MAOB 1128/4885 |
| US-20180309067-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | ORC3, EZH1, BMI1 | ALOX5 1376/4885MAOA 2319/4885MAOB 2503/4885 |
| US-20210408398-A1 | HOLE TRANSPORT MATERIAL, PREPARATION METHOD THEREOF, AND ORGANIC LIGHT-EMITTING DEVICE | SLC39A3, SOD1, SLC39A11 | ALOX5 1900/4885MAOA 1527/4885MAOB 1002/4885 |
| US-10790455-B2 | Organic electroluminescent materials and devices | ORC3, ALKBH2, ENPP3 | ALOX5 1488/4885MAOA 2570/4885MAOB 609/4885 |
| US-20230192665-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | OCIAD2, OCIAD1, ODC1 | ALOX5 535/4885MAOA 68/4885MAOB 10/4885 |
| US-11038137-B2 | Organic electroluminescent materials and devices | ORC3, NUDC, AOC1 | ALOX5 1328/4885MAOA 2370/4885MAOB 1762/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.