Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19859062 | 0.84 | MAPT (0.57) | LMNAGFERKMT2AL3MBTL1RECQL | |
| SCHEMBL14741800 | 0.84 | MAPT (0.57) | LMNAGFERKMT2AL3MBTL1RECQL | |
| SCHEMBL30935544 | 0.84 | MAPT (0.57) | LMNAGFERKMT2AL3MBTL1RECQL | |
| SCHEMBL16367706 | 0.83 | LMNA (0.66) | LMNAGFERKMT2AL3MBTL1RECQL | |
| SCHEMBL7971868 | 0.83 | LMNA (0.66) | LMNAGFERKMT2AL3MBTL1RECQL | |
| SCHEMBL17737724 | 0.83 | LMNA (0.66) | LMNAGFERKMT2AL3MBTL1RECQL | |
| SCHEMBL7399083 | 0.82 | L3MBTL1 (0.47) | LMNAGFERKMT2AL3MBTL1RECQL | |
| SCHEMBL24988733 | 0.80 | ALDH1A1 (0.45) | LMNAGFERKMT2ARECQLTDP1 | |
| SCHEMBL2726619 | 0.78 | LMNA (0.51) | LMNAGFERKMT2AL3MBTL1RECQL | |
| SCHEMBL2569248 | 0.78 | LMNA (0.47) | LMNAGFERKMT2AL3MBTL1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018015458-A1 | MICROBIOCIDAL OXADIAZOLE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2018-01-25 | — | — | WO | disclosed |