Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | EIF4A1 | P60842 | 1/20 | 0.35 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22022375 | 0.83 | SKP2 (0.32) | SKP2 | |
| SCHEMBL20176727 | 0.80 | RAB9A (0.42) | RAB9AKDM4ESMN1; SMN2MAPTMEN1 | |
| SCHEMBL17694341 | 0.78 | KDM4E (0.43) | RAB9AKDM4ESMN1; SMN2MAPTMEN1 | |
| SCHEMBL20176717 | 0.76 | KDM4E (0.41) | RAB9AKDM4ESMN1; SMN2MAPTMEN1 | |
| SCHEMBL20176724 | 0.75 | KDM4E (0.40) | RAB9AKDM4ESMN1; SMN2MAPTMEN1 | |
| SCHEMBL16546613 | 0.75 | KDM4E (0.40) | RAB9AKDM4ESMN1; SMN2MAPTMEN1 | |
| SCHEMBL22022427 | 0.75 | MCHR1 (0.34) | TLR7APP | |
| SCHEMBL20176733 | 0.74 | KDM4E (0.39) | RAB9AKDM4ESMN1; SMN2MAPTMEN1 | |
| SCHEMBL14703079 | 0.73 | RARB (0.53) | RAB9AKDM4ESMN1; SMN2MAPTMEN1 | |
| SCHEMBL17694344 | 0.73 | RARB (0.38) | RAB9AKDM4ESMN1; SMN2MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3487955-B1 | LIQUID CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2020-05-20 | — | — | EP | disclosed |
| WO-2018015320-A1 | LIQUID CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2018-01-25 | — | — | WO | disclosed |