SCHEMBL197985

SCHEMBL197985

CSCC[C@@H](C(=O)O)N(C)C

nearest known ligand 0.52

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
RNPEP Q9H4A4 1/20 0.52
FOLH1 Q04609 2/20 0.40
FNTA P49354 2/20 0.36
FNTB P49356 2/20 0.36
LMNA P02545 2/20 0.36
CHRNB2 P17787 1/20 0.34
CHRNB4 P30926 1/20 0.34
CHRNA3 P32297 1/20 0.34
CHRNA4 P43681 1/20 0.34
ALDH1A1 P00352 2/20 0.33
NPSR1 Q6W5P4 1/20 0.33
KDM4E B2RXH2 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
USP2 O75604 1/20 0.33
TSHR P16473 1/20 0.33
PKM P14618 1/20 0.33
GAA P10253 1/20 0.33
MAPK1 P28482 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL197984 1.00 RNPEP (0.52) RNPEPFOLH1FNTAFNTBLMNA
SCHEMBL28090080 0.85 RNPEP (0.50) RNPEPFOLH1FNTAFNTBLMNA
SCHEMBL28186076 0.83 RNPEP (0.53) RNPEPFOLH1FNTAFNTBLMNA
SCHEMBL2872371 0.83 RNPEP (0.52) RNPEPFOLH1FNTAFNTBLMNA
SCHEMBL2872370 0.83 RNPEP (0.52) RNPEPFOLH1FNTAFNTBLMNA
SCHEMBL19545996 0.83 RNPEP (0.42) RNPEPFOLH1CHRNB2CHRNB4CHRNA3
SCHEMBL9781791 0.82 RNPEP (0.52) RNPEPFOLH1FNTAFNTBLMNA
SCHEMBL9781788 0.82 RNPEP (0.52) RNPEPFOLH1FNTAFNTBLMNA
Hydrochloric Acid SCHEMBL5680481 0.82 RNPEP (0.52) RNPEPFOLH1FNTAFNTBLMNA
SCHEMBL22384085 0.82 RNPEP (0.47) RNPEPFOLH1FNTAFNTBLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160244484-A1 ANTI-INFLAMMATORY TRIPEPTIDES DR. AUGUST WOLFF GMBH & CO. KG ARZNEIMITTEL (DE) 2016-08-25 US claimed
EP-3049428-A1 ANTI-INFLAMMATORY TRIPEPTIDES Dr. August Wolff GmbH & Co. KG Arzneimittel (DE) 2016-08-03 EP claimed
CN-105102475-A Sodium channel sensitive conopeptides and analogs, including compositions and methods thereof UNIV UTAH RES FOUND 2015-11-25 CN claimed
WO-2015040235-A1 ANTI-INFLAMMATORY TRIPEPTIDES DR. AUGUST WOLFF GMBH & CO. KG ARZNEIMITTEL (DE) 2015-03-26 WO claimed
US-20210087593-A1 N-ALKYLATION OF ALKALOID COMPOUNDS WILLOW BIOSCIENCES INC (CA) 2021-03-25 US disclosed
US-10954269-B2 Anti-inflammatory tripeptides DR. AUGUST WOLFF GMBH & CO. KG ARZNEIMITTEL (DE) 2021-03-23 US disclosed
US-10676767-B2 Methods and compositions for making ephedrine and related alkaloid compounds Willow Biosciences Inc. (CA) 2020-06-09 US disclosed
US-20190153029-A1 ANTI-INFLAMMATORY TRIPEPTIDES DR. AUGUST WOLFF GMBH & CO. KG ARZNEIMITTEL (DE) 2019-05-23 US disclosed
US-10227379-B2 Anti-inflammatory tripeptides DR. AUGUST WOLFF GMBH & CO. KG ARZNEIMITTEL (DE) 2019-03-12 US disclosed
US-20180179561-A1 Methods and Compositions For Making Ephedrine and Related Alkaloid Compounds Willow Biosciences Inc. (CA) 2018-06-28 US disclosed
EP-3314001-A1 METHODS AND COMPOSITIONS FOR MAKING EPHEDRINE AND RELATED ALKALOID COMPOUNDS Serturner Corp. (CA) 2018-05-02 EP disclosed
WO-2016205939-A1 METHODS AND COMPOSITIONS FOR MAKING EPHEDRINE AND RELATED ALKALOID COMPOUNDS SERTURNER CORP. (CA) 2016-12-29 WO disclosed
CN-101365716-B Mu-conotoxin peptides and their use as local anesthetics ATHERIS LAB 2014-07-16 CN disclosed
US-8158330-B2 Resist protective coating composition and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2012-04-17 US disclosed
US-8088537-B2 Resist top coat composition and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2012-01-03 US disclosed
US-20090286182-A1 RESIST PROTECTIVE COATING COMPOSITION AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2009-11-19 US disclosed
US-20090197200-A1 Resist top coat composition and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2009-08-06 US disclosed
CN-101365716-A Mu-conotoxin peptides and their use as local anesthetics ATHERIS LAB (CH) 2009-02-11 CN disclosed
US-5744678-A NICKEL COMPOUND, ORGANOPHOSPHORUS COMPOUND, ORGANOALUMINUM COMPOUND, CARBON-HALOGEN COMPOUNDS; CATALYST SELECTIVITY NIPPON OIL CO., LTD. (JP) 1998-04-28 US disclosed
EP-0758563-A1 OLEFIN OLIGOMERIZATION CATALYST AND PROCESS FOR THE PREPARATION OF OLEFIN OLIGOMER USING IT NIPPON OIL COMPANY, LTD. (JP) 1997-02-19 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160244484-A1 ANTI-INFLAMMATORY TRIPEPTIDES VIP, TNF, ENPEP RNPEP 85/4885FOLH1 173/4885FNTA 1133/4885
US-20190153029-A1 ANTI-INFLAMMATORY TRIPEPTIDES VIP, TNF, ENPEP RNPEP 85/4885FOLH1 173/4885FNTA 1133/4885
US-10954269-B2 Anti-inflammatory tripeptides VIP, TNF, ENPEP RNPEP 85/4885FOLH1 173/4885FNTA 1133/4885
US-10676767-B2 Methods and compositions for making ephedrine and related alkaloid compounds PNMT, GNMT, BHMT RNPEP 502/4885FOLH1 871/4885FNTA 470/4885
US-10227379-B2 Anti-inflammatory tripeptides VIP, TNF, ENPEP RNPEP 85/4885FOLH1 173/4885FNTA 1133/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.