Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC9 | O60706 | 1/20 | 0.31 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.31 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.31 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.31 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.31 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31180315 | 0.80 | CYP11B1 (0.31) | CYP11B1CYP11B2PDE3BPDE3A | |
| SCHEMBL27076357 | 0.79 | ABCC9 (0.33) | ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL4297627 | 0.74 | TDP2 (0.46) | — | |
| SCHEMBL29961692 | 0.73 | MMP12 (0.38) | — | |
| SCHEMBL27076356 | 0.73 | MMP12 (0.38) | — | |
| SCHEMBL13726349 | 0.72 | KIF11 (0.46) | CYP11B1CYP11B2 | |
| SCHEMBL30496989 | 0.70 | KDM4E (0.39) | ABCC9ABCC8KCNJ11KCNJ8PDE3B | |
| SCHEMBL286550 | 0.70 | KDM4E (0.39) | ABCC9ABCC8KCNJ11KCNJ8PDE3B | |
| SCHEMBL27076383 | 0.70 | MEN1 (0.39) | CYP11B1CYP11B2 | |
| SCHEMBL787497 | 0.69 | CYP11B1 (0.51) | CYP11B1CYP11B2PDE3BPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024222814-A1 | CYP11B2 INHIBITOR COMPOUND, PHARMACEUTICAL COMPOSITION AND USE THEREOF | 长春金赛药业有限责任公司 | 2024-10-31 | — | — | WO | disclosed |
| WO-2018017490-A1 | CARBAMATE QUINABACTIN | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2018-01-25 | — | — | WO | disclosed |