Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ALPL | P05186 | 1/20 | 0.45 |
| ▸ | ALPI | P09923 | 1/20 | 0.45 |
| ▸ | SYK | P43405 | 2/20 | 0.45 |
| ▸ | CTSS | P25774 | 1/20 | 0.44 |
| ▸ | CTSK | P43235 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | XDH | P47989 | 1/20 | 0.42 |
| ▸ | SDHB | P21912 | 2/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19805931 | 0.85 | MEN1 (0.45) | MEN1KMT2AALDH1A1L3MBTL1KDM4E | |
| SCHEMBL3557728 | 0.81 | LMNA (0.55) | MEN1KMT2ACTSSCTSKALDH1A1 | |
| SCHEMBL22912193 | 0.81 | SDHB (0.60) | MEN1KMT2AALDH1A1L3MBTL1KDM4E | |
| SCHEMBL22912197 | 0.81 | MEN1 (0.49) | MEN1KMT2AALDH1A1L3MBTL1KDM4E | |
| SCHEMBL30484391 | 0.80 | XDH (0.51) | CTSSCTSKL3MBTL1XDHIDO1 | |
| SCHEMBL19806057 | 0.80 | MEN1 (0.51) | MEN1KMT2ASYKALDH1A1L3MBTL1 | |
| SCHEMBL21379948 | 0.80 | XDH (0.51) | CTSSCTSKL3MBTL1XDHIDO1 | |
| SCHEMBL9792857 | 0.80 | CTSS (0.47) | CTSSCTSKXDHIDO1 | |
| SCHEMBL29976351 | 0.80 | MEN1 (0.51) | MEN1KMT2ASYKALDH1A1L3MBTL1 | |
| SCHEMBL9792887 | 0.80 | CTSS (0.47) | CTSSCTSKXDHIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3484854-B1 | APOPTOSIS INHIBITORS | NAT INSTITUTE OF BIOLOGICAL SCIENCES BEIJING (CN) | 2021-01-20 | — | — | EP | disclosed |
| WO-2018014802-A1 | APOPTOSIS INHIBITORS | NATIONAL INSTITUTE OF BIOLOGICAL SCIENCES, BEIJING (CN) | 2018-01-25 | — | — | WO | disclosed |