Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.48 |
| ▸ | HTR2C | P28335 | 2/20 | 0.48 |
| ▸ | HTR2B | P41595 | 2/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | TUBB1 | Q9H4B7 | 4/20 | 0.41 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.41 |
| ▸ | TUBB | P07437 | 3/20 | 0.41 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.41 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.41 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.41 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.41 |
| ▸ | TUBB3 | Q13509 | 3/20 | 0.41 |
| ▸ | TUBB2A | Q13885 | 3/20 | 0.41 |
| ▸ | TUBB8 | Q3ZCM7 | 3/20 | 0.41 |
| ▸ | TUBA3E | Q6PEY2 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3764427 | 0.88 | MAPT (0.50) | HTR2AHTR2CHTR2BPTGS2HSD17B10 | |
| SCHEMBL1122521 | 0.86 | PTGS2 (0.64) | HTR2AHTR2CHTR2BPTGS2HSD17B10 | |
| SCHEMBL19806073 | 0.85 | HTR2A (0.48) | HTR2AHTR2CHTR2BPTGS2MAPT | |
| SCHEMBL29976346 | 0.85 | HTR2A (0.48) | HTR2AHTR2CHTR2BPTGS2MAPT | |
| SCHEMBL17610643 | 0.82 | CYP4F2 (0.42) | HTR2AHTR2CHTR2BHSD17B10ALOX15 | |
| SCHEMBL22817375 | 0.81 | CYP4F2 (0.41) | HTR2AHTR2CHTR2BHSD17B10ALOX15 | |
| SCHEMBL17655662 | 0.80 | PTGS2 (0.52) | HTR2AHTR2CHTR2BPTGS2HSD17B10 | |
| SCHEMBL1055709 | 0.80 | MGAM (0.45) | HSD17B10ALDH1A1 | |
| SCHEMBL31063117 | 0.79 | HSD17B10 (0.49) | HSD17B10ALOX15TSHRMAPTCYP4F2 | |
| SCHEMBL16411031 | 0.79 | THRB (0.44) | HTR2AHTR2CPTGS2MAPTCYP4F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260124173-A1 | THERAPEUTIC ALKALOID COMPOUNDS | SENSORIUM THERAPEUTICS INC (US) | 2026-05-07 | — | — | US | disclosed |
| US-20250304533-A1 | THERAPEUTIC ALKALOID COMPOUNDS | SENSORIUM THERAPEUTICS, INC. | 2025-10-02 | — | — | US | disclosed |
| US-12410128-B1 | Therapeutic alkaloid compounds | SENSORIUM THERAPEUTICS, INC. (US) | 2025-09-09 | — | — | US | disclosed |
| WO-2025101939-A1 | THERAPEUTIC ALKALOID COMPOUNDS | SENSORIUM THERAPEUTICS, INC. (US) | 2025-05-15 | — | — | WO | disclosed |
| US-4803225-A | Dihydroxy-phenethylamino compounds useful as pharmaceuticals | FISONS, PLC (GB) | 1989-02-07 | — | — | US | disclosed |
| US-4720586-A | Substituted 3,4-dihydroxy-phenylethylamino compounds | FISONS, PLC (GB) | 1988-01-19 | — | — | US | disclosed |
| EP-0142283-A2 | Phenylethylamines, process for their preparation and compositions containing them | FISONS plc (GB) | 1985-05-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250304533-A1 | THERAPEUTIC ALKALOID COMPOUNDS | HTR3B, MTNR1B, PNMT | HTR2A 65/4885HTR2C 107/4885HTR2B 80/4885 |
| US-20260124173-A1 | THERAPEUTIC ALKALOID COMPOUNDS | ADRA1B, HTR1B, ADRB1 | HTR2A 38/4885HTR2C 37/4885HTR2B 9/4885 |
| US-12410128-B1 | Therapeutic alkaloid compounds | HTR3B, MTNR1B, PNMT | HTR2A 65/4885HTR2C 107/4885HTR2B 80/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.