Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 4/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.40 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.40 |
| ▸ | CDC42 | P60953 | 1/20 | 0.40 |
| ▸ | RAC1 | P63000 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.40 |
| ▸ | HPGDS | O60760 | 5/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | GLA | P06280 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4933136 | 0.74 | ALDH1A1 (0.33) | CYP1A2TSHRALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL1980666 | 0.72 | HDAC6 (0.50) | CYP1A2ALDH1A1HPGDCYP2C19RAB9A | |
| SCHEMBL4929686 | 0.71 | PDK1 (0.45) | AKR1C3AKR1C2TSHRALDH1A1GLA | |
| SCHEMBL14820094 | 0.71 | ALDH1A1 (0.38) | HPGDSALDH1A1GLAHPGDF2 | |
| SCHEMBL1492745 | 0.69 | AKR1C3 (0.67) | PTGS2AKR1C3AKR1C2PTGS1CDC42 | |
| Hydrochloric Acid SCHEMBL2698899 | 0.68 | AKR1C3 (0.65) | PTGS2AKR1C3AKR1C2PTGS1CDC42 | |
| SCHEMBL30778131 | 0.66 | AKR1C3 (0.55) | PTGS2AKR1C3AKR1C2PTGS1CDC42 | |
| SCHEMBL31240242 | 0.64 | PTGS2 (0.53) | PTGS2AKR1C3AKR1C2PTGS1CDC42 | |
| SCHEMBL22031514 | 0.64 | PTGS2 (0.53) | PTGS2AKR1C3AKR1C2PTGS1CDC42 | |
| SCHEMBL28654157 | 0.64 | ALDH1A1 (0.36) | PTGS2AKR1C3AKR1C2PTGS1CDC42 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2318402-B1 | Pyrrolidinyl-alkyl-amide derivatives their preparation and their therapeutic application as CCR3 receptor ligands | SANOFI SA (FR) | 2014-04-30 | — | — | EP | disclosed |
| US-8420636-B2 | Pyrrolidinyl-alkyl-amide derivatives, their preparation, and their therapeutic application as CCR3 receptor ligands | SANOFI (FR) | 2013-04-16 | — | — | US | disclosed |
| US-20110144104-A1 | PYRROLIDINYL-ALKYL-AMIDE DERIVATIVES, THEIR PREPARATION, AND THEIR THERAPEUTIC APPLICATION AS CCR3 RECEPTOR LIGANDS | SANOFI-AVENTIS (FR) | 2011-06-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110144104-A1 | PYRROLIDINYL-ALKYL-AMIDE DERIVATIVES, THEIR PREPARATION, AND THEIR THERAPEUTIC APPLICATION AS CCR3 RECEPTOR LIGANDS | CCR3, CCR1, CCR4 | PPARA 326/4885PTGS2 1963/4885AKR1C3 1400/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.