Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | STING1 | Q86WV6 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7167832 | 0.74 | ALDH1A1 (0.37) | MAPTALDH1A1SMN1; SMN2L3MBTL1MEN1 | |
| SCHEMBL4933138 | 0.73 | HDAC6 (0.53) | HDAC6MAPTALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL1980665 | 0.72 | PPARA (0.41) | ALDH1A1POLBSMN1; SMN2GAAALOX15 | |
| SCHEMBL4929694 | 0.71 | HDAC6 (0.53) | HDAC6MAPTALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL14820094 | 0.70 | ALDH1A1 (0.38) | MAPTALDH1A1POLBSMN1; SMN2GAA | |
| SCHEMBL2910400 | 0.68 | HDAC6 (0.50) | HDAC6MAPTALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL6781352 | 0.68 | MGAM (0.38) | HDAC6MAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL1514591 | 0.67 | HDAC6 (1.00) | HDAC6MAPTALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL591634 | 0.66 | MTNR1A (0.68) | HDAC6POLBFFAR1L3MBTL1LMNA | |
| SCHEMBL31496381 | 0.66 | STING1 (0.53) | ALDH1A1HTTSTING1HPGDCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2318402-B1 | Pyrrolidinyl-alkyl-amide derivatives their preparation and their therapeutic application as CCR3 receptor ligands | SANOFI SA (FR) | 2014-04-30 | — | — | EP | disclosed |
| US-8420636-B2 | Pyrrolidinyl-alkyl-amide derivatives, their preparation, and their therapeutic application as CCR3 receptor ligands | SANOFI (FR) | 2013-04-16 | — | — | US | disclosed |
| US-20110144104-A1 | PYRROLIDINYL-ALKYL-AMIDE DERIVATIVES, THEIR PREPARATION, AND THEIR THERAPEUTIC APPLICATION AS CCR3 RECEPTOR LIGANDS | SANOFI-AVENTIS (FR) | 2011-06-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110144104-A1 | PYRROLIDINYL-ALKYL-AMIDE DERIVATIVES, THEIR PREPARATION, AND THEIR THERAPEUTIC APPLICATION AS CCR3 RECEPTOR LIGANDS | CCR3, CCR1, CCR4 | HDAC6 351/4885MAPT 3947/4885ALDH1A1 2212/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.