Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7831752 | 0.89 | ALOX15 (0.57) | HDAC6ALOX15HTTSMN1; SMN2AKR1B1 | |
| SCHEMBL15920638 | 0.78 | POLB (0.59) | HTTSMN1; SMN2AKR1B1HPGDRAB9A | |
| SCHEMBL7835421 | 0.77 | HDAC1 (0.49) | HDAC6LMNAPKMHSD17B10ALOX5 | |
| SCHEMBL14421725 | 0.77 | PDK1 (0.53) | ALOX15HTTSMN1; SMN2AKR1B1HPGD | |
| SCHEMBL1269672 | 0.76 | SMN1; SMN2 (0.82) | HDAC6ALOX15HTTSMN1; SMN2HPGD | |
| SCHEMBL4933138 | 0.76 | HDAC6 (0.53) | HDAC6ALOX15HTTSMN1; SMN2HPGD | |
| SCHEMBL4364056 | 0.74 | MAPT (0.54) | HTTSMN1; SMN2AKR1B1RAB9ALMNA | |
| SCHEMBL7829595 | 0.74 | L3MBTL1 (0.49) | LMNAPOLBL3MBTL1MAPTALDH1A1 | |
| SCHEMBL2175795 | 0.74 | PDK1 (0.53) | HTTSMN1; SMN2AKR1B1HPGDRAB9A | |
| SCHEMBL2179891 | 0.74 | UBE2T (0.55) | HTTSMN1; SMN2AKR1B1HPGDRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080287434-A1 | New amino-alkyl-amide derivatives as CCR3 receptor ligands | SANOFI-AVENTIS (FR) | 2008-11-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080287434-A1 | New amino-alkyl-amide derivatives as CCR3 receptor ligands | CCR3, CCR1, CCR4 | HDAC6 782/4885ALOX15 3100/4885HTT 4829/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.