Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CARM1 | Q86X55 | 5/20 | 0.98 |
| ▸ | AMD1 | P17707 | 4/20 | 0.98 |
| ▸ | PCMT1 | P22061 | 3/20 | 0.85 |
| ▸ | PRMT5 | O14744 | 3/20 | 0.85 |
| ▸ | PRMT1 | Q99873 | 3/20 | 0.85 |
| ▸ | NSD3 | Q9BZ95 | 2/20 | 0.85 |
| ▸ | PRMT3 | O60678 | 2/20 | 0.85 |
| ▸ | PNMT | P11086 | 2/20 | 0.85 |
| ▸ | PRMT6 | Q96LA8 | 2/20 | 0.85 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.85 |
| ▸ | PRMT7 | Q9NVM4 | 2/20 | 0.85 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.85 |
| ▸ | KDR | P35968 | 1/20 | 0.85 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.85 |
| ▸ | NNMT | P40261 | 3/20 | 0.71 |
| ▸ | DOT1L | Q8TEK3 | 5/20 | 0.70 |
| ▸ | NSD2 | O96028 | 3/20 | 0.70 |
| ▸ | SETD7 | Q8WTS6 | 3/20 | 0.70 |
| ▸ | EHMT2 | Q96KQ7 | 3/20 | 0.70 |
| ▸ | TRDMT1 | O14717 | 2/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ademetionine SCHEMBL2007787 | 0.99 | CARM1 (1.00) | CARM1AMD1PCMT1PRMT5PRMT1 | |
| Ademetionine SCHEMBL7810282 | 0.99 | CARM1 (1.00) | CARM1AMD1PCMT1PRMT5PRMT1 | |
| Ademetionine SCHEMBL3202538 | 0.99 | CARM1 (1.00) | CARM1AMD1PCMT1PRMT5PRMT1 | |
| Ademetionine SCHEMBL4164615 | 0.99 | CARM1 (1.00) | CARM1AMD1PCMT1PRMT5PRMT1 | |
| Ademetionine SCHEMBL599664 | 0.99 | CARM1 (1.00) | CARM1AMD1PCMT1PRMT5PRMT1 | |
| Ademetionine SCHEMBL600368 | 0.99 | CARM1 (1.00) | CARM1AMD1PCMT1PRMT5PRMT1 | |
| Ademetionine SCHEMBL66767 | 0.99 | CARM1 (1.00) | CARM1AMD1PCMT1PRMT5PRMT1 | |
| Ademetionine SCHEMBL59293 | 0.99 | CARM1 (1.00) | CARM1AMD1PCMT1PRMT5PRMT1 | |
| Ademetionine SCHEMBL55479 | 0.99 | CARM1 (1.00) | CARM1AMD1PCMT1PRMT5PRMT1 | |
| Ademetionine SCHEMBL13033865 | 0.99 | CARM1 (1.00) | CARM1AMD1PCMT1PRMT5PRMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110150820-A1 | METHODS FOR COVALENTLY ATTACHING A POLYMER TO A METHIONINE RESIDUE IN PROTEINS AND PEPTIDES | INSIGHT BIOPHARMACEUTICALS LTD. (IL) | 2011-06-23 | — | — | US | disclosed |
| WO-2010023670-A2 | METHODS FOR COVALENTLY ATTACHING A POLYMER TO A METHIONINE RESIDUE IN PROTEINS AND PEPTIDES | INSIGHT BIOPHARMACEUTICALS LTD. (IL) | 2010-03-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110150820-A1 | METHODS FOR COVALENTLY ATTACHING A POLYMER TO A METHIONINE RESIDUE IN PROTEINS AND PEPTIDES | LNPEP, MGMT, DNPEP | CARM1 1627/4885AMD1 82/4885PCMT1 75/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.