SCHEMBL19816622

SCHEMBL19816622

NC(=O)OCC(=O)N1CCOC(=O)C1

nearest known ligand 0.39

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.39
RAB9A P51151 6/20 0.37
POLB P06746 1/20 0.37
LMNA P02545 1/20 0.36
NPC1 O15118 3/20 0.36
ALDH1A1 P00352 4/20 0.36
SMN1; SMN2 Q16637 3/20 0.36
KDM4E B2RXH2 2/20 0.36
GLA P06280 2/20 0.36
GAA P10253 1/20 0.36
TDP1 Q9NUW8 2/20 0.35
FKBP1A P62942 1/20 0.35
ATM Q13315 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28647633 0.86 L3MBTL1 (0.41) L3MBTL1RAB9APOLBLMNANPC1
SCHEMBL18292192 0.83 L3MBTL1 (0.41) L3MBTL1RAB9APOLBLMNANPC1
SCHEMBL18288674 0.79 L3MBTL1 (0.47) L3MBTL1RAB9APOLBLMNANPC1
SCHEMBL18288667 0.76 L3MBTL1 (0.37) L3MBTL1RAB9APOLBLMNANPC1
SCHEMBL28685062 0.76 L3MBTL1 (0.66) L3MBTL1RAB9APOLBLMNANPC1
SCHEMBL29366921 0.76 ALDH1A1 (0.33) POLBALDH1A1SMN1; SMN2GAA
SCHEMBL19820847 0.75 NAAA (0.39) RAB9APOLBLMNANPC1ALDH1A1
SCHEMBL29257691 0.72 NAAA (0.44) L3MBTL1RAB9APOLBLMNAALDH1A1
SCHEMBL23753775 0.72 MEN1 (0.40) LMNASMN1; SMN2
SCHEMBL23798617 0.70 CNR2 (0.32) POLBLMNAALDH1A1SMN1; SMN2GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113573740-A Mixed lytic cell penetrating complexes for nucleic acid delivery 利兰斯坦福初级大学董事会 2021-10-29 CN disclosed
EP-3490562-A1 IMMOLATIVE CELL-PENETRATING COMPLEXES FOR NUCLEIC ACID DELIVERY The Board of Trustees of the Leland Stanford Junior University (US) 2019-06-05 EP disclosed
WO-2018022930-A1 IMMOLATIVE CELL-PENETRATING COMPLEXES FOR NUCLEIC ACID DELIVERY THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2018-02-01 WO disclosed