Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 7/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.36 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.36 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.36 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 3/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18292192 | 0.92 | L3MBTL1 (0.41) | L3MBTL1ATMTDP1CTDSP1APOBEC3A | |
| SCHEMBL18644053 | 0.88 | — | — | |
| SCHEMBL18288674 | 0.87 | L3MBTL1 (0.47) | L3MBTL1ATMTDP1CTDSP1APOBEC3A | |
| SCHEMBL18567001 | 0.79 | L3MBTL1 (0.32) | L3MBTL1ATMTDP1CTDSP1APOBEC3A | |
| SCHEMBL19816622 | 0.76 | L3MBTL1 (0.39) | L3MBTL1ATMTDP1KDM4EALDH1A1 | |
| SCHEMBL18288656 | 0.75 | ALOX15 (0.32) | L3MBTL1KDM4EALDH1A1LMNAHPGD | |
| SCHEMBL18352024 | 0.75 | KEAP1 (0.32) | L3MBTL1KDM4EALDH1A1GAAMAPT | |
| SCHEMBL18288692 | 0.71 | L3MBTL1 (0.63) | L3MBTL1TDP1KDM4EALDH1A1GAA | |
| SCHEMBL18199355 | 0.71 | ALDH1A1 (0.30) | ALDH1A1MAPT | |
| SCHEMBL23082073 | 0.70 | BLM (0.37) | ALDH1A1LMNARAB9APOLBNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160355464-A1 | FUMARATE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND METHODS OF USE | Nguyen, Mark Quang (US) | 2016-12-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160355464-A1 | FUMARATE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND METHODS OF USE | FH, FPGS, APC | L3MBTL1 4164/4885ATM 4406/4885TDP1 1164/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.