Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 2/20 | 0.36 |
| ▸ | KIF11 | P52732 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | TDO2 | P48775 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | TACR1 | P25103 | 1/20 | 0.31 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.30 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.30 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | CASP3 | P42574 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16943655 | 0.91 | RIPK1 (0.33) | RIPK1KIF11TACR1 | |
| SCHEMBL12500683 | 0.74 | HDAC4 (0.44) | KIF11MAPK1IDO1TDO2ALDH1A1 | |
| SCHEMBL19820891 | 0.73 | RIPK1 (0.41) | RIPK1KIF11CYP2C19HIF1ATAAR1 | |
| SCHEMBL15893491 | 0.73 | ESR1 (0.46) | RIPK1MAPK1CYP2C19HIF1AALDH1A1 | |
| SCHEMBL19820873 | 0.73 | RIPK1 (0.41) | RIPK1KIF11CYP2C19HIF1ATAAR1 | |
| SCHEMBL16943652 | 0.72 | KIF11 (0.38) | KIF11MAPK1CYP2C19HIF1ATACR1 | |
| SCHEMBL16943654 | 0.72 | KIF11 (0.33) | KIF11CYP2C19LMNA | |
| SCHEMBL15617016 | 0.71 | KIF11 (0.33) | KIF11MAPK1IDO1TDO2TAAR1 | |
| SCHEMBL3001776 | 0.70 | RIPK1 (0.49) | RIPK1MAPK1CYP2C19HIF1ATAAR1 | |
| SCHEMBL44954 | 0.68 | MAPK1 (0.44) | KIF11MAPK1TAAR1ALDH1A1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170240493-A1 | NOVEL POLYISOBUTYLENE-BASED THERMOPLASTIC ELASTOMERS | THE UNIVERSITY OF AKRON (US) | 2017-08-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170240493-A1 | NOVEL POLYISOBUTYLENE-BASED THERMOPLASTIC ELASTOMERS | TERB1, TERT, TRRAP | RIPK1 1667/4885KIF11 3172/4885MAPK1 4668/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.