Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.57 |
| ▸ | PAOX | Q6QHF9 | 5/20 | 0.44 |
| ▸ | CASP2 | P42575 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | S1PR2 | O95136 | 5/20 | 0.40 |
| ▸ | S1PR4 | O95977 | 5/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.40 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.40 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25802613 | 0.91 | ALOX5 (0.53) | ALOX5PAOXCASP2ALDH1A1TSHR | |
| SCHEMBL18954297 | 0.85 | ALOX5 (0.54) | ALOX5CASP2ALDH1A1TSHRS1PR2 | |
| SCHEMBL6655161 | 0.85 | PAOX (0.57) | PAOXCASP2ALDH1A1TSHRS1PR2 | |
| SCHEMBL13616526 | 0.85 | PAOX (0.57) | PAOXCASP2ALDH1A1TSHRS1PR2 | |
| SCHEMBL13616527 | 0.85 | PAOX (0.57) | PAOXCASP2ALDH1A1TSHRS1PR2 | |
| SCHEMBL21360967 | 0.83 | ALDH1A1 (0.54) | ALOX5ALDH1A1TSHRS1PR2S1PR4 | |
| SCHEMBL24398981 | 0.81 | ALDH1A1 (0.52) | ALOX5PAOXALDH1A1TSHRS1PR2 | |
| SCHEMBL24176090 | 0.81 | ALDH1A1 (0.52) | ALOX5ALDH1A1TSHRS1PR2S1PR4 | |
| SCHEMBL16090830 | 0.80 | ALOX5 (0.62) | ALOX5PAOXALDH1A1TSHRTRPV1 | |
| SCHEMBL18650257 | 0.79 | ALOX5 (0.62) | ALOX5ALDH1A1TSHRTRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180147298-A1 | COMPOSITIONS AND METHODS FOR DELIVERY OF AGENTS | MODERNATX, INC. (US) | 2018-05-31 | — | — | US | disclosed |
| US-20180028664-A1 | COMPOSITIONS AND METHODS FOR DELIVERY OF AGENTS | MODERNATX, INC. (US) | 2018-02-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180147298-A1 | COMPOSITIONS AND METHODS FOR DELIVERY OF AGENTS | HDLBP, APOB, TSG101 | ALOX5 3206/4885PAOX 3175/4885CASP2 3941/4885 |
| US-20180028664-A1 | COMPOSITIONS AND METHODS FOR DELIVERY OF AGENTS | HDLBP, APOB, TSG101 | ALOX5 3206/4885PAOX 3175/4885CASP2 3941/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.