SCHEMBL1982192

SCHEMBL1982192

O=C1C=Cc2c([nH]c3ccccc23)C1=O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 7/20 0.47
ALDH1A1 P00352 6/20 0.47
HPGD P15428 3/20 0.47
HTT P42858 3/20 0.47
LMNA P02545 2/20 0.47
GAA P10253 2/20 0.47
SMN1; SMN2 Q16637 2/20 0.47
GLA P06280 1/20 0.47
ATM Q13315 1/20 0.47
CYP1A2 P05177 4/20 0.44
HSD17B10 Q99714 3/20 0.44
MEN1 O00255 3/20 0.44
KMT2A Q03164 3/20 0.44
GPR3 P46089 2/20 0.44
PARP1 P09874 2/20 0.44
TNKS2 Q9H2K2 2/20 0.44
TNKS O95271 1/20 0.44
BLM P54132 1/20 0.44
PMP22 Q01453 1/20 0.44
PARP15 Q460N3 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30174328 1.00 KDM4E (0.47) KDM4EALDH1A1HPGDHTTLMNA
SCHEMBL3151147 0.88 KDM4E (0.50) KDM4EALDH1A1HPGDHTTLMNA
SCHEMBL29757961 0.81 ALDH1A1 (0.44) KDM4EALDH1A1HPGDHTTLMNA
SCHEMBL7726806 0.72 CDC25A (0.51) KDM4EALDH1A1HPGDHTTLMNA
SCHEMBL28841465 0.72 CCR6 (0.47) KDM4EALDH1A1HPGDHTTLMNA
Carbazole SCHEMBL28181847 0.69 ALDH1A1 (0.61) KDM4EALDH1A1HPGDHTTLMNA
SCHEMBL21561768 0.69 ALDH1A1 (0.56) KDM4EALDH1A1HPGDHTTLMNA
SCHEMBL16620312 0.68 PARP1 (0.54) KDM4EALDH1A1HPGDHTTLMNA
SCHEMBL11793572 0.67 CES1 (0.50) KDM4EALDH1A1HPGDLMNACYP1A2
SCHEMBL30288157 0.67 CES1 (0.50) KDM4EALDH1A1HPGDLMNACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024067670-A1 ANTIBODY AND CONJUGATE 苏州智核生物医药科技有限公司 2024-04-04 WO claimed
CN-115322206-A Condensed dioxy heterocorrole compound and preparation method thereof 湖南科技大学 2022-11-11 CN claimed
WO-2024067670-A1 ANTIBODY AND CONJUGATE 苏州智核生物医药科技有限公司 2024-04-04 WO disclosed
CN-115850449-A Antibodies and conjugates 苏州智核生物医药科技有限公司 2023-03-28 CN disclosed
CN-115322206-A Condensed dioxy heterocorrole compound and preparation method thereof 湖南科技大学 2022-11-11 CN disclosed
EP-2509948-B1 PHOTOINITIATORS FOR UV-LED CURABLE COMPOSITIONS AND INKS AGFA GRAPHICS NV (BE) 2017-05-03 EP disclosed
US-9431616-B2 Phosphaphenanthrene-carbazole-based organic light-emitting compound, and organic light-emitting device comprising same INKTEC CO., LTD. (KR) 2016-08-30 US disclosed
EP-2510400-B1 UV-LED CURABLE COMPOSITIONS AND INKS AGFA GRAPHICS NV (BE) 2015-04-29 EP disclosed
US-8957224-B2 Photoinitiators for UV-LED curable compositions and inks AGFA GRAPHICS NV (BE) 2015-02-17 US disclosed
US-8569393-B2 UV-LED curable compositions and inks AGFA-GEVAERT N.V. (BE) 2013-10-29 US disclosed
US-20130161603-A1 PHOSPHAPHENANTHRENE-CARBAZOLE-BASED ORGANIC LIGHT-EMITTING COMPOUND, AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME INKTEC CO., LTD. (KR) 2013-06-27 US disclosed
US-20120309861-A1 PHOTOINITIATORS FOR UV-LED CURABLE COMPOSITIONS AND INKS AGFA-GEVAERT N.V. (BE) 2012-12-06 US disclosed
US-20120283349-A1 UV-LED CURABLE COMPOSITIONS AND INKS AGFA-GEVAERT N.V. (BE) 2012-11-08 US disclosed
EP-2509948-A1 PHOTOINITIATORS FOR UV-LED CURABLE COMPOSITIONS AND INKS Agfa-Gevaert (BE) 2012-10-17 EP disclosed
EP-2510400-A1 UV-LED CURABLE COMPOSITIONS AND INKS Agfa-Gevaert (BE) 2012-10-17 EP disclosed
WO-2011069943-A1 UV-LED CURABLE COMPOSITIONS AND INKS AGFA-GEVAERT (BE) 2011-06-16 WO disclosed
WO-2011069947-A1 PHOTOINITIATORS FOR UV-LED CURABLE COMPOSITIONS AND INKS AGFA-GEVAERT (BE) 2011-06-16 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120309861-A1 PHOTOINITIATORS FOR UV-LED CURABLE COMPOSITIONS AND INKS WEE1, CBX4, USP9X KDM4E 1156/4885ALDH1A1 1029/4885HPGD 3146/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.