SCHEMBL19821977

SCHEMBL19821977

CCC(C)C(=O)OCCNC(=O)NC

nearest known ligand 0.54

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KEAP1 Q14145 1/20 0.37
NFE2L2 Q16236 1/20 0.37
TSHR P16473 2/20 0.36
KMT2A Q03164 2/20 0.34
MEN1 O00255 1/20 0.34
MAPT P10636 1/20 0.34
HSD17B10 Q99714 1/20 0.34
EPHX1 P07099 2/20 0.33
IARS1 P41252 2/20 0.32
EPHX2 P34913 1/20 0.32
CHRNB2 P17787 2/20 0.32
CHRNA4 P43681 2/20 0.32
CHRNB4 P30926 1/20 0.32
CHRNA3 P32297 1/20 0.32
ACHE P22303 1/20 0.32
KDM4E B2RXH2 1/20 0.32
USP2 O75604 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19821958 0.90 TSHR (0.44) KEAP1NFE2L2TSHRMAPTHSD17B10
SCHEMBL12243264 0.84 CHRNB2 (0.41) TSHRKMT2AMEN1MAPTHSD17B10
SCHEMBL26418570 0.84 TSHR (0.36) TSHRKMT2AMEN1MAPTHSD17B10
SCHEMBL19821954 0.81 KEAP1 (0.32) KEAP1NFE2L2HSD17B10CHRNB2CHRNA4
SCHEMBL19821882 0.81 MAPK1 (0.40) TSHRKMT2AMEN1HSD17B10KDM4E
SCHEMBL15499961 0.81 CYP2D6 (0.39) TSHRKMT2AMEN1IARS1CHRNB2
SCHEMBL14153997 0.81 KMT2A (0.44) TSHRKMT2AMEN1HSD17B10IARS1
SCHEMBL12619025 0.81 KDM4E (0.35) TSHRKMT2AMEN1HSD17B10EPHX1
SCHEMBL12134872 0.80 ALDH1A1 (0.42) TSHRKMT2AMEN1MAPTHSD17B10
SCHEMBL12134710 0.80 IARS1 (0.35) TSHRKMT2AMEN1IARS1CHRNB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11773266-B2 Polymer, molded body, foam, resin composition, and production method for polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2023-10-03 US disclosed
US-20230129965-A1 HYDROPHILIC AND OLEOPHOBIC POLYMER SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2023-04-27 US disclosed
US-20180030175-A1 POLYMER SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-02-01 US disclosed