Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | TRPA1 | O75762 | 9/20 | 0.43 |
| ▸ | XPO1 | O14980 | 2/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 3/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.33 |
| ▸ | MIF | P14174 | 2/20 | 0.33 |
| ▸ | BACH1 | O14867 | 1/20 | 0.33 |
| ▸ | MAFK | O60675 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | NAAA | Q02083 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25331937 | 1.00 | ALDH1A1 (0.46) | ALDH1A1LMNATP53TRPA1XPO1 | |
| SCHEMBL5334903 | 0.72 | — | — | |
| SCHEMBL25332113 | 0.67 | — | — | |
| SCHEMBL18225463 | 0.67 | — | — | |
| SCHEMBL432819 | 0.67 | — | — | |
| SCHEMBL432818 | 0.67 | — | — | |
| SCHEMBL22561649 | 0.67 | TRPA1 (0.46) | ALDH1A1LMNATP53TRPA1XPO1 | |
| SCHEMBL3793670 | 0.66 | — | — | |
| SCHEMBL994470 | 0.64 | TRPA1 (0.43) | TRPA1XPO1NAAA | |
| SCHEMBL2937706 | 0.64 | TRPA1 (0.43) | TRPA1XPO1NAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180029979-A1 | ISOTHIOCYANATE COMPOUND AND APPLICATION THEREOF | DRIVINGFORCE THERAPEUTICS Co., Ltd. (CN) | 2018-02-01 | — | — | US | disclosed |
| US-20180029979-A1 | ISOTHIOCYANATE COMPOUND AND APPLICATION THEREOF | DRIVINGFORCE THERAPEUTICS Co., Ltd. (CN) | 2018-02-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180029979-A1 | ISOTHIOCYANATE COMPOUND AND APPLICATION THEREOF | XPO1, XPOT, XPO4 | ALDH1A1 2991/4885LMNA 4192/4885TP53 2198/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.