SCHEMBL432819

SCHEMBL432819

CSC=CCCN=C=S

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL432818 1.00
Erucin SCHEMBL7579439 0.86 TRPA1 (0.68)
SCHEMBL1074724 0.77
SCHEMBL1074725 0.77
SCHEMBL5334903 0.75
SCHEMBL25332113 0.70
SCHEMBL22561649 0.70 TRPA1 (0.46)
SCHEMBL2937706 0.67 TRPA1 (0.43)
SCHEMBL25331937 0.67 ALDH1A1 (0.46)
SCHEMBL19822549 0.67 ALDH1A1 (0.46)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 85 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4580612-A1 USE OF NRF2 ACTIVATORS FOR THE TREATMENT OF CEREBRAL SMALL VESSEL DISEASE Institut National de la Santé et de la Recherche Médicale (FR) 2025-07-09 EP claimed
WO-2024047248-A1 USE OF NRF2 ACTIVATORS FOR THE TREATMENT OF CEREBRAL SMALL VESSEL DISEASE Institut National de la Santé et de la Recherche Médicale (FR) 2024-03-07 WO claimed
CN-115491272-A Preparation method of dual-purpose characteristic-free spicy fresh radish juice fermentation base liquid with peel and product thereof 中国农业科学院麻类研究所 2022-12-20 CN claimed
US-20210069159-A1 Bach1 Inhibitors in Combination with Nrf2 Activators and Pharmaceutical Compositions Thereof VTV THERAPEUTICS LLC 2021-03-11 US claimed
US-10898475-B2 Bach1 inhibitors in combination with Nrf2 activators and pharmaceutical compositions thereof VTV THERAPEUTICS LLC (US) 2021-01-26 US claimed
US-20170231967-A1 Bach1 Inhibitors in Combination with Nrf2 Activators and Pharmaceutical Compositions Thereof VTV THERAPEUTICS LLC 2017-08-17 US claimed
WO-2016089648-A1 BACH 1 INHIBITORS IN COMBINATION WITH NRF2 ACTIVATORS AND PHARMACEUTICAL COMPOSITIONS THEREOF VTV THERAPEUTICS LLC (US) 2016-06-09 WO claimed
US-20100086658-A1 LOW FAT CONSUMER PRODUCT COMPRISING A NATURAL PRESERVATIVE SYSTEM AND A METHOD FOR MAKING THE SAME CONOPCO, INC. D/B/A UNILEVER 2010-04-08 US claimed
EP-2163238-A2 Compound for lightening skin tone comprising sulforaphane or sulforaphene or their derivates Henkel AG & Co. KGaA (DE) 2010-03-17 EP claimed
EP-2120611-A1 A LOW FAT CONSUMER PRODUCT COMPRISING A NATURAL PRESERVATIVE SYSTEM AND A METHOD FOR MAKING THE SAME UNILEVER N.V. (NL) 2009-11-25 EP claimed
WO-2008098804-A1 A LOW FAT CONSUMER PRODUCT COMPRISING A NATURAL PRESERVATIVE SYSTEM AND A METHOD FOR MAKING THE SAME UNILEVER N.V. (NL) 2008-08-21 WO claimed
US-20080193615-A1 LOW FAT CONSUMER PRODUCT COMPRISING A NATURAL PRESERVATIVE SYSTEM AND A METHOD FOR MAKING THE SAME CONOPCO, INC., D/B/A UNILEVER (US) 2008-08-14 US claimed
WO-2002087388-A1 CONTAINER FOR CLEANING IMPLEMENTS, IN ADDITION TO AN INSERTION BODY, TOOTHBRUSH AND RESERVOIR NEUFELD KLAUS (AT) 2002-11-07 WO claimed
EP-4746880-A2 METHODS OF TREATING DILATED CARDIOMYOPATHY Regencor, Inc. (US) 2026-05-27 EP disclosed
US-20260034107-A1 SUBSTITUTED FUSED IMIDAZOLE DERIVATIVES AND METHODS OF TREATING SICKLE CELL DISEASE AND RELATED COMPLICATIONS VTV THERAPEUTICS LLC (US) 2026-02-05 US disclosed
EP-4580612-A1 USE OF NRF2 ACTIVATORS FOR THE TREATMENT OF CEREBRAL SMALL VESSEL DISEASE Institut National de la Santé et de la Recherche Médicale (FR) 2025-07-09 EP disclosed
EP-1217312-A2 Air conditioner and method for inhibiting mold growth in said air conditioner MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 2002-06-26 EP disclosed
US-20020061352-A1 Products comprising an isothiocyanate preservative system and methods of their use ALBION LABORATORIES, INC. (FORMERLY ALBION INTERNATIONAL, INC.) 2002-05-23 US disclosed
US-6361812-B1 WITH PRESERVATIVES SELECTED FROM SORBATE AND BENZOATE PRESERVATIVES; FOR FOOD OR BEVERAGE PRODUCTS THE PROCTER & GAMBLE CO. 2002-03-26 US disclosed
WO-2001035769-A1 PRODUCTS COMPRISING AN ISOTHIOCYANATE PRESERVATIVE SYSTEM AND METHODS OF THEIR USE THE PROCTER & GAMBLE COMPANY (US) 2001-05-25 WO disclosed