Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 12/20 | 0.46 |
| ▸ | NAAA | Q02083 | 1/20 | 0.40 |
| ▸ | XPO1 | O14980 | 2/20 | 0.38 |
| ▸ | MIF | P14174 | 4/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | BACH1 | O14867 | 1/20 | 0.31 |
| ▸ | MAFK | O60675 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.31 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5334903 | 0.75 | — | — | |
| SCHEMBL25332113 | 0.70 | — | — | |
| SCHEMBL432818 | 0.70 | — | — | |
| SCHEMBL432819 | 0.70 | — | — | |
| SCHEMBL2937706 | 0.67 | TRPA1 (0.43) | TRPA1NAAAXPO1 | |
| SCHEMBL994470 | 0.67 | TRPA1 (0.43) | TRPA1NAAAXPO1 | |
| SCHEMBL25331937 | 0.67 | ALDH1A1 (0.46) | TRPA1NAAAXPO1MIFALDH1A1 | |
| SCHEMBL19822549 | 0.67 | ALDH1A1 (0.46) | TRPA1NAAAXPO1MIFALDH1A1 | |
| SCHEMBL6481787 | 0.66 | — | — | |
| SCHEMBL93753 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3519470-B1 | PHOSPHAGUANIDINE GROUP IV METAL OLEFIN POLYMERIZATION CATALYSTS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2020-10-21 | — | — | EP | disclosed |