SCHEMBL19825818

SCHEMBL19825818

CC(C)C(=O)[C@H](CN)NC(=O)[C@@H](NC(=O)C(CCN)C1CCCCC1)C(C)O

nearest known ligand 0.35

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ CPB2 Q96IY4 7/20 0.35
▸ TP53 P04637 1/20 0.32
▸ MEN1 O00255 1/20 0.32
▸ MITF O75030 1/20 0.32
▸ KMT2A Q03164 1/20 0.32
▸ KDM4E B2RXH2 1/20 0.31
▸ GMNN O75496 1/20 0.31
▸ LMNA P02545 1/20 0.31
▸ MAPT P10636 1/20 0.31
▸ BLM P54132 1/20 0.31
▸ PMP22 Q01453 1/20 0.31
▸ SMN1; SMN2 Q16637 1/20 0.31
▸ ALDH1A1 P00352 1/20 0.31
▸ MMP1 P03956 1/20 0.30
▸ FCER2 P06734 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23658150 1.00 CPB2 (0.35) CPB2TP53MEN1MITFKMT2A
SCHEMBL19825813 0.94 CPB2 (0.36) CPB2MEN1MITFKMT2AMMP1
SCHEMBL19825856 0.92 TP53 (0.34) CPB2TP53KDM4EGMNNLMNA
SCHEMBL23658165 0.92 TP53 (0.34) CPB2TP53KDM4EGMNNLMNA
SCHEMBL18637457 0.91 CPB2 (0.35) CPB2TP53MEN1MITFKMT2A
SCHEMBL19825887 0.91 CPB2 (0.35) CPB2TP53MEN1MITFKMT2A
SCHEMBL26675669 0.89 CPB2 (0.34) CPB2TP53MEN1MITFKMT2A
SCHEMBL19825890 0.87 CPB2 (0.36) CPB2MEN1MITFKMT2AMMP1
SCHEMBL21335134 0.87 TP53 (0.36) CPB2TP53KDM4EGMNNLMNA
SCHEMBL19825816 0.85 CPB2 (0.35) CPB2MEN1MITFKMT2AMMP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230340026-A1 COMPOUNDS NEW PHARMA LICENCE HOLDINGS LTD (MT) 2023-10-26 — — US disclosed
US-20180030092-A1 COMPOUNDS SPERO THERAPEUTICS, INC. 2018-02-01 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230340026-A1 COMPOUNDS BCAT1, BCAT2, CCNT1 CPB2 1430/4885TP53 1956/4885MEN1 1609/4885
US-20180030092-A1 COMPOUNDS BCAT1, BCAT2, IL4I1 CPB2 1924/4885TP53 1950/4885MEN1 1503/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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