Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NRP1 | O14786 | 2/20 | 0.33 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.31 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19826065 | 0.96 | NRP1 (0.34) | NRP1 | |
| SCHEMBL18637058 | 0.96 | NRP1 (0.34) | NRP1 | |
| SCHEMBL19825867 | 0.92 | NRP1 (0.31) | NRP1 | |
| SCHEMBL18637056 | 0.89 | NRP1 (0.34) | NRP1SIRT6SIRT1 | |
| SCHEMBL19825858 | 0.88 | BCHE (0.30) | — | |
| SCHEMBL19825875 | 0.87 | NRP1 (0.34) | NRP1 | |
| SCHEMBL18637415 | 0.87 | NRP1 (0.34) | NRP1 | |
| SCHEMBL19825876 | 0.82 | NRP1 (0.34) | NRP1 | |
| SCHEMBL18637416 | 0.82 | NRP1 (0.34) | NRP1 | |
| SCHEMBL22105960 | 0.80 | NRP1 (0.38) | NRP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180030092-A1 | COMPOUNDS | SPERO THERAPEUTICS, INC. | 2018-02-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180030092-A1 | COMPOUNDS | BCAT1, BCAT2, IL4I1 | NRP1 2404/4885SIRT6 1992/4885SIRT1 1245/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.