SCHEMBL25650263

SCHEMBL25650263

CCCOc1c(F)cc(F)cc1F

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CCNB2 O95067 1/20 0.36
CCNE2 O96020 1/20 0.36
CDK1 P06493 1/20 0.36
CDK4 P11802 1/20 0.36
CCNB1 P14635 1/20 0.36
CCND1 P24385 1/20 0.36
CCNE1 P24864 1/20 0.36
CDK2 P24941 1/20 0.36
CCND2 P30279 1/20 0.36
CCND3 P30281 1/20 0.36
CCNB3 Q8WWL7 1/20 0.36
FFAR1 O14842 2/20 0.34
GRIN2D O15399 1/20 0.34
GRIN3B O60391 1/20 0.34
GRIN1 Q05586 1/20 0.34
GRIN2A Q12879 1/20 0.34
GRIN2B Q13224 1/20 0.34
GRIN2C Q14957 1/20 0.34
GRIN3A Q8TCU5 1/20 0.34
MEN1 O00255 4/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28601432 0.86 GRIN2D (0.33) CCNB2CCNE2CDK1CDK4CCNB1
SCHEMBL13087963 0.83 GRIN2D (0.33) FFAR1GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL14524684 0.81 HTR2A (0.38) FFAR1GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL15295192 0.81 FFAR4 (0.48) CCNB2CCNE2CDK1CDK4CCNB1
SCHEMBL15295228 0.78 HRH3 (0.38) ALDH1A1HTTKDM4EFFAR4HPGD
SCHEMBL14723882 0.78 KDM7A (0.32) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL29115841 0.78 LPL (0.33) FFAR1GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL15295193 0.77 L3MBTL1 (0.41) CCNB2CCNE2CDK1CDK4CCNB1
SCHEMBL19795478 0.77 ALDH1A1 (0.37) FFAR1MEN1ALDH1A1KMT2AHTT
SCHEMBL8242910 0.77 THRA (0.47) CCNB2CCNE2CDK1CDK4CCNB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023114516-A2 CELL-PERMEANT INHIBITORS OF VIRAL CYSTEINE PROTEASES THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2023-06-22 WO disclosed