Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 8/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.46 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.46 |
| ▸ | TNKS | O95271 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12204565 | 0.86 | SMN1; SMN2 (0.62) | SLC9A1SMN1; SMN2RAB9AKCNMA1KEAP1 | |
| SCHEMBL23470944 | 0.84 | SMN1; SMN2 (0.48) | SLC9A1SMN1; SMN2RAB9AKCNMA1KEAP1 | |
| SCHEMBL13925150 | 0.83 | SMN1; SMN2 (0.50) | SLC9A1SMN1; SMN2RAB9AKCNMA1KEAP1 | |
| SCHEMBL12970540 | 0.83 | KCNMA1 (0.50) | SLC9A1SMN1; SMN2RAB9AKCNMA1KEAP1 | |
| SCHEMBL24861808 | 0.83 | SMN1; SMN2 (0.50) | SLC9A1SMN1; SMN2RAB9AKCNMA1KEAP1 | |
| SCHEMBL28332052 | 0.83 | SMN1; SMN2 (0.50) | SLC9A1SMN1; SMN2RAB9AKCNMA1KEAP1 | |
| SCHEMBL24046811 | 0.83 | GAA (0.49) | SLC9A1SMN1; SMN2RAB9AKCNMA1KEAP1 | |
| SCHEMBL172700 | 0.81 | ALDH1A1 (0.56) | SLC9A1SMN1; SMN2RAB9AKCNMA1KEAP1 | |
| SCHEMBL15632082 | 0.80 | SMN1; SMN2 (0.57) | SLC9A1SMN1; SMN2RAB9AKCNMA1KEAP1 | |
| SCHEMBL24081163 | 0.80 | SLC9A1 (0.44) | SLC9A1SMN1; SMN2RAB9AKCNMA1KEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024112727-A1 | TREATING PAIN ASSOCIATED WITH CENTRAL SENSITIZATION | MEDICON PHARMACEUTICALS, INC. (US) | 2024-05-30 | — | — | WO | disclosed |
| WO-2018022978-A1 | CERTAIN (2S)-N-[(1S)-1-CYANO-2-PHENYLETHYL]-1,4-OXAZEPANE-2-CARBOXAMIDES FOR TREATING BRONCHIECTASIS | INSMED INCORPORATED (US) | 2018-02-01 | — | — | WO | disclosed |