Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.37 |
| ▸ | SMYD2 | Q9NRG4 | 2/20 | 0.33 |
| ▸ | ACHE | P22303 | 6/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 8/20 | 0.32 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10099917 | 0.95 | PAOX (0.36) | PAOXACHE | |
| SCHEMBL8739604 | 0.95 | ACHE (0.39) | PAOXACHEHRH3KCNH2 | |
| SCHEMBL8738807 | 0.91 | PAOX (0.38) | PAOXACHE | |
| SCHEMBL25820446 | 0.91 | PAOX (0.38) | PAOXACHE | |
| SCHEMBL19829897 | 0.90 | PAOX (0.37) | PAOXACHE | |
| SCHEMBL8739618 | 0.89 | PAOX (0.38) | PAOXACHEHRH3 | |
| SCHEMBL25820457 | 0.88 | PAOX (0.39) | PAOXACHEHRH3 | |
| SCHEMBL8739109 | 0.88 | THRA (0.40) | PAOXACHE | |
| SCHEMBL26872388 | 0.88 | ACHE (0.36) | PAOXACHEHRH3 | |
| SCHEMBL8738445 | 0.86 | PAOX (0.38) | PAOXHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180177881-A1 | Multicomponent Degradable Cationic Polymers | THE JOHNS HOPKINS UNIVERSITY | 2018-06-28 | — | — | US | disclosed |
| US-9884118-B2 | Multicomponent degradable cationic polymers | THE JOHNS HOPKINS UNIVERSITY (US) | 2018-02-06 | — | — | US | disclosed |
| US-20180028455-A1 | PEPTIDE/PARTICLE DELIVERY SYSTEMS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2018-02-01 | — | — | US | disclosed |
| US-20170143639-A1 | NANOCOMPOSITES OF GOLD AND POLYMERS | THE JOHNS HOPKINS UNIVERSITY (US) | 2017-05-25 | — | — | US | disclosed |
| US-20150272900-A1 | Layer-By-Layer Approach to Co-Deliver DNA and siRNA via AuNPs: A Potential Platform for Modifying Release Kinetics | THE JOHNS HOPKINS UNIVERSITY | 2015-10-01 | — | — | US | disclosed |
| US-20150250881-A1 | Multicomponent Degradable Cationic Polymers | THE JOHNS HOPKINS UNIVERSITY (US) | 2015-09-10 | — | — | US | disclosed |
| US-20140294909-A1 | NANOCOMPOSITES OF GOLD AND POLYMERS | THE JOHNS HOPKINS UNIVERSITY (US) | 2014-10-02 | — | — | US | disclosed |
| US-20120128782-A1 | Multicomponent Degradable Cationic Polymers | THE JOHNS HOPKINS UNIVERSITY (US) | 2012-05-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150272900-A1 | Layer-By-Layer Approach to Co-Deliver DNA and siRNA via AuNPs: A Potential Platform for Modifying Release Kinetics | DNMT3L, DBNL, HNRNPL | PAOX 4804/4885SMYD2 1487/4885ACHE 1104/4885 |
| US-20150250881-A1 | Multicomponent Degradable Cationic Polymers | PEF1, FIBP, PARN | PAOX 1525/4885SMYD2 1791/4885ACHE 4465/4885 |
| US-20180177881-A1 | Multicomponent Degradable Cationic Polymers | PEF1, FIBP, PARN | PAOX 1525/4885SMYD2 1791/4885ACHE 4465/4885 |
| US-20170143639-A1 | NANOCOMPOSITES OF GOLD AND POLYMERS | HNRNPL, HNRNPLL, ACSL3 | PAOX 4172/4885SMYD2 3009/4885ACHE 1213/4885 |
| US-20120128782-A1 | Multicomponent Degradable Cationic Polymers | PEF1, FIBP, PARN | PAOX 1525/4885SMYD2 1791/4885ACHE 4465/4885 |
| US-20180028455-A1 | PEPTIDE/PARTICLE DELIVERY SYSTEMS | VEGFA, IAPP, FLT1 | PAOX 3116/4885SMYD2 4456/4885ACHE 4729/4885 |
| US-20140294909-A1 | NANOCOMPOSITES OF GOLD AND POLYMERS | HNRNPL, HNRNPLL, ACSL3 | PAOX 4172/4885SMYD2 3009/4885ACHE 1213/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.