Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.70 |
| ▸ | NPC1 | O15118 | 5/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.70 |
| ▸ | TP53 | P04637 | 1/20 | 0.70 |
| ▸ | RECQL | P46063 | 1/20 | 0.65 |
| ▸ | POLB | P06746 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 6/20 | 0.55 |
| ▸ | CLK1 | P49759 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | F2 | P00734 | 1/20 | 0.51 |
| ▸ | PLG | P00747 | 1/20 | 0.51 |
| ▸ | PLAU | P00749 | 1/20 | 0.51 |
| ▸ | PLAT | P00750 | 1/20 | 0.51 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.51 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | CASP3 | P42574 | 1/20 | 0.50 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23367925 | 0.84 | RAB9A (0.72) | RAB9ANPC1SMN1; SMN2TP53RECQL | |
| SCHEMBL11651472 | 0.83 | RAB9A (1.00) | RAB9ANPC1SMN1; SMN2TP53RECQL | |
| SCHEMBL23602 | 0.80 | RAB9A (1.00) | RAB9ANPC1SMN1; SMN2TP53RECQL | |
| SCHEMBL27971290 | 0.78 | RAB9A (0.70) | RAB9ANPC1SMN1; SMN2TP53RECQL | |
| SCHEMBL3587933 | 0.78 | POLB (0.74) | RAB9ANPC1SMN1; SMN2TP53POLB | |
| SCHEMBL15096727 | 0.78 | POLB (1.00) | RAB9ANPC1SMN1; SMN2POLBMAPT | |
| SCHEMBL2878844 | 0.77 | RAB9A (0.69) | RAB9ANPC1SMN1; SMN2TP53RECQL | |
| SCHEMBL2883601 | 0.77 | RAB9A (0.69) | RAB9ANPC1SMN1; SMN2TP53RECQL | |
| SCHEMBL2093226 | 0.76 | CA2 (0.58) | RAB9ANPC1SMN1; SMN2TP53MAPT | |
| SCHEMBL13956819 | 0.76 | RAB9A (0.56) | RAB9ANPC1SMN1; SMN2TP53RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10315998-B2 | Amide compound and the preparation method and use thereof | SHENYANG SINOCHEM AGROCHEMICALS R&D CO., LTD. (CN) | 2019-06-11 | — | — | US | disclosed |
| EP-3293179-A1 | AMIDE COMPOUND AND THE PREPARATION METHOD AND USE THEREOF | Shenyang Sinochem Agrochemicals R & D Co., Ltd. (CN) | 2018-03-14 | — | — | EP | disclosed |
| US-20180029991-A1 | AMIDE COMPOUND AND THE PREPARATION METHOD AND USE THEREOF | Shenyang Sinochem Agrochemicals R&D Co., LTD (CN) | 2018-02-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10315998-B2 | Amide compound and the preparation method and use thereof | CYP51A1, ERG28, NAT1 | RAB9A 1568/4885NPC1 577/4885SMN1; SMN2 3374/4885 |
| US-20180029991-A1 | AMIDE COMPOUND AND THE PREPARATION METHOD AND USE THEREOF | CYP51A1, ERG28, NAT1 | RAB9A 1568/4885NPC1 577/4885SMN1; SMN2 3374/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.