Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 11/20 | 0.51 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | MAT2A | P31153 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.45 |
| ▸ | ELANE | P08246 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19831032 | 0.94 | MAPK1 (0.52) | MAPK8MAPK9MAPK1ALDH1A1MAT2A | |
| SCHEMBL19831212 | 0.92 | MAPK8 (0.50) | MAPK8MAPK9MAPK1ALDH1A1ELANE | |
| SCHEMBL19831051 | 0.89 | PPARG (0.48) | MAPK8MAPK1ALDH1A1GAAMAPT | |
| SCHEMBL19831040 | 0.88 | MAPK8 (0.52) | MAPK8MAPK1ALDH1A1MAPT | |
| SCHEMBL19831089 | 0.87 | MAPK1 (0.50) | MAPK8MAPK9MAPK1ALDH1A1MAPT | |
| SCHEMBL19831072 | 0.85 | MAPK1 (0.48) | MAPK8MAPK1ALDH1A1MAPTMAT2A | |
| SCHEMBL19831088 | 0.84 | ENPP2 (0.48) | MAPK8MAPK9MAPTMAT2AENPP2 | |
| SCHEMBL19831091 | 0.83 | ELANE (0.54) | MAPK1ALDH1A1GAAMAPTELANE | |
| SCHEMBL19831098 | 0.80 | ELANE (0.45) | MAPK8MAPK1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL19831123 | 0.80 | MMP2 (0.45) | MAPK8MAPK1ALDH1A1GAAELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018021762-A1 | NOVEL COMPOUND, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | 현대약품 주식회사 | 2018-02-01 | — | — | WO | disclosed |