Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | USP14 | P54578 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MAT2A | P31153 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19831032 | 0.91 | MAPK1 (0.52) | MAPK1USP14HPGDALDH1A1HTT | |
| SCHEMBL19831035 | 0.85 | MAPK8 (0.51) | MAPK1MAPTALDH1A1SMN1; SMN2MAT2A | |
| SCHEMBL19831040 | 0.85 | MAPK8 (0.52) | MAPK1MAPTUSP14HPGDALDH1A1 | |
| SCHEMBL19831071 | 0.83 | SRD5A2 (0.41) | MAPTUSP14NPSR1MAPK8ALOX15 | |
| SCHEMBL19831104 | 0.83 | MAPT (0.47) | MAPK1MAPTHTTKDM4ENPSR1 | |
| SCHEMBL19831212 | 0.82 | MAPK8 (0.50) | MAPK1USP14ALDH1A1LMNAKMT2A | |
| SCHEMBL19831089 | 0.81 | MAPK1 (0.50) | MAPK1MAPTUSP14HPGDALDH1A1 | |
| SCHEMBL19831051 | 0.79 | PPARG (0.48) | MAPK1MAPTALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL19831123 | 0.79 | MMP2 (0.45) | MAPK1ALDH1A1KDM4EELANENPC1 | |
| SCHEMBL19831091 | 0.78 | ELANE (0.54) | MAPK1MAPTHPGDALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018021762-A1 | NOVEL COMPOUND, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | 현대약품 주식회사 | 2018-02-01 | — | — | WO | disclosed |