Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 3/20 | 0.40 |
| ▸ | RORC | P51449 | 1/20 | 0.39 |
| ▸ | MIF | P14174 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | DHODH | Q02127 | 1/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | USP14 | P54578 | 2/20 | 0.38 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | FNTA | P49354 | 1/20 | 0.36 |
| ▸ | FNTB | P49356 | 1/20 | 0.36 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19831033 | 0.89 | MAPK8 (0.45) | SRD5A2PPARGRORCNOTUMUSP14 | |
| SCHEMBL19831088 | 0.84 | ENPP2 (0.48) | PPARGRORCMAPTMAPK8 | |
| SCHEMBL19831072 | 0.83 | MAPK1 (0.48) | MAPTNPSR1USP14MAPK8ALOX15 | |
| SCHEMBL19831041 | 0.81 | MAPK8 (0.52) | PPARGMAPTNPSR1USP14MAPK8 | |
| SCHEMBL19831105 | 0.80 | CCR2 (0.48) | PPARGMAPTMAPK8ALOX15TSHR | |
| SCHEMBL19831112 | 0.80 | MAPK8 (0.42) | PPARGNOTUMUSP14MAPK8 | |
| SCHEMBL19831246 | 0.78 | MAPK8 (0.41) | PPARGNOTUMUSP14MAPK8 | |
| SCHEMBL30360562 | 0.77 | LMNA (0.42) | MAPTNPSR1ALOX15TSHRFNTA | |
| SCHEMBL19831047 | 0.77 | PPARG (0.53) | SRD5A2PPARGMAPTNPSR1 | |
| SCHEMBL19831223 | 0.77 | RORC (0.41) | PPARGRORCUSP14MAPK8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018021762-A1 | NOVEL COMPOUND, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | 현대약품 주식회사 | 2018-02-01 | — | — | WO | disclosed |