Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 3/20 | 0.48 |
| ▸ | TP53 | P04637 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.46 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.45 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19831091 | 0.92 | ELANE (0.54) | ELANETP53MAPTALDH1A1MEN1 | |
| SCHEMBL19831198 | 0.87 | PPARG (0.48) | MAPTPPARGALDH1A1HPGDMAPK8 | |
| SCHEMBL19831040 | 0.83 | MAPK8 (0.52) | MAPTPPARGALDH1A1HPGDMAPK8 | |
| SCHEMBL19831214 | 0.81 | PPARG (0.53) | ELANEPPARGMAPK8 | |
| SCHEMBL19831032 | 0.76 | MAPK1 (0.52) | ELANEALDH1A1HPGDMAPK8NPSR1 | |
| SCHEMBL6855830 | 0.76 | PPARG (0.53) | ELANEMAPTPPARGCNR1 | |
| SCHEMBL19831093 | 0.76 | RORC (0.49) | ALDH1A1MEN1KMT2ANPSR1 | |
| SCHEMBL19831035 | 0.75 | MAPK8 (0.51) | ELANEMAPTALDH1A1GAAMAPK8 | |
| SCHEMBL19831065 | 0.75 | MAPK8 (0.47) | TP53MAPTPPARGMEN1HPGD | |
| SCHEMBL19831212 | 0.74 | MAPK8 (0.50) | ELANETP53ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018021762-A1 | NOVEL COMPOUND, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | 현대약품 주식회사 | 2018-02-01 | — | — | WO | disclosed |