Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 2/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | P2RX3 | P56373 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | CCR3 | P51677 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19831224 | 0.87 | MAPK8 (0.48) | MAPK8PPARGTP53MEN1KMT2A | |
| SCHEMBL19831040 | 0.85 | MAPK8 (0.52) | MAPK8PPARGP2RX3MAPTCYP1A2 | |
| SCHEMBL19831199 | 0.81 | CCR3 (0.44) | MAPK8CCR3HPGDHTTAKR1C3 | |
| SCHEMBL19831197 | 0.81 | ALDH1A1 (0.46) | MAPK8MAPTCCR3TP53MEN1 | |
| SCHEMBL19831098 | 0.78 | ELANE (0.45) | MAPK8MAPTCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL19831032 | 0.78 | MAPK1 (0.52) | MAPK8HPGDHTTALOX15TSHR | |
| SCHEMBL19831099 | 0.75 | ELANE (0.48) | MAPK8PPARGMAPTTP53MEN1 | |
| SCHEMBL19831072 | 0.74 | MAPK1 (0.48) | MAPK8MAPTKMT2AHPGDHTT | |
| SCHEMBL19831067 | 0.74 | ALOX15 (0.53) | MAPTMEN1KMT2AHPGDHTT | |
| SCHEMBL10095274 | 0.73 | TP53 (0.55) | PPARGMAPTCYP1A2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018021762-A1 | NOVEL COMPOUND, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | 현대약품 주식회사 | 2018-02-01 | — | — | WO | disclosed |