Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | DPP4 | P27487 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.40 |
| ▸ | MET | P08581 | 4/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | RNASEH1 | O60930 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | DAO | P14920 | 1/20 | 0.35 |
| ▸ | DDO | Q99489 | 1/20 | 0.35 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.34 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.34 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16098758 | 0.85 | USP2 (0.44) | MEN1NPC1RAB9AKMT2AMET | |
| SCHEMBL1986500 | 0.82 | LMNA (0.48) | MEN1NPC1RAB9AKMT2AKDM4E | |
| SCHEMBL14335694 | 0.80 | CYP19A1 (0.42) | MEN1KMT2ACYP1A2CYP3A4CYP2C19 | |
| SCHEMBL1982721 | 0.78 | TP53 (0.46) | MEN1NPC1RAB9AKMT2AALDH1A1 | |
| SCHEMBL3359777 | 0.77 | MEN1 (0.43) | MEN1NPC1RAB9AKMT2AADRA2A | |
| SCHEMBL1033282 | 0.77 | GRIN2D (0.43) | MEN1KMT2ADPP4KDM4E | |
| SCHEMBL5809605 | 0.73 | RPA1 (0.49) | MEN1NPC1RAB9AKMT2AKDM4E | |
| SCHEMBL8321684 | 0.72 | MEN1 (0.43) | MEN1NPC1RAB9AKMT2AADRA2A | |
| SCHEMBL2483507 | 0.71 | KDM4E (0.50) | NPC1RAB9AKMT2ACYP3A4KDM4E | |
| SCHEMBL28759223 | 0.70 | DPP4 (0.69) | MEN1KMT2ADPP4CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970129-A2 | CRYSTALS OF LAQUINIMOD SODIUM AND IMPROVED PROCESS FOR THE MANUFACTURE THEREOF | Teva Pharmaceutical Industries Ltd. (IL) | 2016-01-20 | — | — | EP | claimed |
| WO-2014153145-A2 | CRYSTALS OF LAQUINIMOD SODIUM AND IMPROVED PROCESS FOR THE MANUFACTURE THEREOF | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2014-09-25 | — | — | WO | claimed |
| EP-2970129-A2 | CRYSTALS OF LAQUINIMOD SODIUM AND IMPROVED PROCESS FOR THE MANUFACTURE THEREOF | Teva Pharmaceutical Industries Ltd. (IL) | 2016-01-20 | — | — | EP | disclosed |
| WO-2014153145-A2 | CRYSTALS OF LAQUINIMOD SODIUM AND IMPROVED PROCESS FOR THE MANUFACTURE THEREOF | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2014-09-25 | — | — | WO | disclosed |
| EP-2337779-A2 | 2-OXO-1,2-DIHYDRO-QUINOLINE MODULATORS OF IMMUNE FUNCTION | Teva Pharmaceutical Industries Ltd. (IL) | 2011-06-29 | — | — | EP | disclosed |
| WO-2010028015-A2 | 2-OXO-1,2-DIHYDRO-QUINOLINE MODULATORS OF IMMUNE FUNCTION | AUSPEX PHARMACEUTICALS, INC (US) | 2010-03-11 | — | — | WO | disclosed |