Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | NQO2 | P16083 | 1/20 | 0.42 |
| ▸ | APLNR | P35414 | 3/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.38 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.38 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14335867 | 0.88 | USP2 (0.44) | CYP19A1NQO2APLNRCA2CA12 | |
| SCHEMBL1983234 | 0.80 | MEN1 (0.43) | KDM4ERNASEH1ALDH1A1HSD17B10MEN1 | |
| SCHEMBL3979257 | 0.76 | CA12 (0.51) | APLNRCA2CA12CA1CA7 | |
| SCHEMBL7826753 | 0.75 | KDM4E (0.38) | APLNRKDM4EHPGDMAPTTDP1 | |
| SCHEMBL16098758 | 0.71 | USP2 (0.44) | CA2CA12CA1CA7CA9 | |
| SCHEMBL6674677 | 0.71 | NQO2 (0.54) | CYP19A1NQO2KDM4EHPGDMAPT | |
| SCHEMBL5809605 | 0.71 | RPA1 (0.49) | KDM4EHPGDMAPTTDP1GAA | |
| SCHEMBL9064266 | 0.69 | CA12 (0.63) | CA2CA12CA1CA7CA9 | |
| SCHEMBL2483507 | 0.69 | KDM4E (0.50) | KDM4EHPGDTDP1ALDH1A1HSD17B10 | |
| SCHEMBL1033282 | 0.69 | GRIN2D (0.43) | KDM4EMAPTTDP1GRIN2DGRIN3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2723340-A1 | DEUTERIUM-ENRICHED 4-HYDROXY-5-METHOXY-N,1-DIMETHYL-2-OXO-N-[(4-TRIFLUORO-METHYL)PHENYL]-1,2-DIHYDROQUINOLINE-3-CARBOXAMIDE | Active Biotech AB (SE) | 2014-04-30 | — | — | EP | claimed |
| WO-2012175541-A1 | DEUTERIUM-ENRICHED 4-HYDROXY-5-METHOXY-N,1-DIMETHYL-2-OXO-N-[(4-TRIFLUORO-METHYL)PHENYL]-1,2-DIHYDROQUINOLINE-3-CARBOXAMIDE | ACTIVE BIOTECH AB (SE) | 2012-12-27 | — | — | WO | claimed |
| EP-2723340-A1 | DEUTERIUM-ENRICHED 4-HYDROXY-5-METHOXY-N,1-DIMETHYL-2-OXO-N-[(4-TRIFLUORO-METHYL)PHENYL]-1,2-DIHYDROQUINOLINE-3-CARBOXAMIDE | Active Biotech AB (SE) | 2014-04-30 | — | — | EP | disclosed |
| WO-2012175541-A1 | DEUTERIUM-ENRICHED 4-HYDROXY-5-METHOXY-N,1-DIMETHYL-2-OXO-N-[(4-TRIFLUORO-METHYL)PHENYL]-1,2-DIHYDROQUINOLINE-3-CARBOXAMIDE | ACTIVE BIOTECH AB (SE) | 2012-12-27 | — | — | WO | disclosed |