SCHEMBL19835504

SCHEMBL19835504

CC(COC(=O)C(N)=O)CC(C)(C)C

nearest known ligand 0.34

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
EGFR P00533 2/20 0.34
TSHR P16473 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16244419 0.84 ALOX15 (0.39) EGFRTSHR
SCHEMBL14991449 0.79 EGFR (0.37) EGFRTSHR
SCHEMBL19221404 0.78 EGFR (0.36) EGFR
SCHEMBL7336059 0.76 MAPT (0.39) EGFRTSHR
SCHEMBL14716655 0.76 EGFR (0.36) EGFR
SCHEMBL29210356 0.74 TSHR (0.58) TSHR
SCHEMBL11750414 0.74 TSHR (0.39) EGFRTSHR
SCHEMBL25899867 0.74 EGFR (0.35) EGFR
SCHEMBL11750771 0.74 TSHR (0.39) EGFRTSHR
Lithium Ion SCHEMBL14716654 0.74 EGFR (0.35) EGFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10478492-B2 Modifications of therapeutic agents for enhanced delivery to target sites CLARIA PARTIKULA LLC (US) 2019-11-19 US disclosed
US-20180028647-A1 MODIFICATIONS OF THERAPEUTIC AGENTS FOR ENHANCED DELIVERY TO TARGET SITES CLARIA ODIN LLC 2018-02-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180028647-A1 MODIFICATIONS OF THERAPEUTIC AGENTS FOR ENHANCED DELIVERY TO TARGET SITES PDK1, PC, PDK2 EGFR 583/4885TSHR 2436/4885
US-10478492-B2 Modifications of therapeutic agents for enhanced delivery to target sites PDK1, PC, PDK2 EGFR 583/4885TSHR 2436/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.