Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | TRPV1 | Q8NER1 | 6/20 | 0.47 |
| ▸ | FOS | P01100 | 1/20 | 0.43 |
| ▸ | TTR | P02766 | 1/20 | 0.43 |
| ▸ | JUN | P05412 | 1/20 | 0.43 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.43 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.43 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.43 |
| ▸ | IARS1 | P41252 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21046217 | 1.00 | ALOX15 (0.49) | ALOX15ALDH1A1GAATSHRNFKB1 | |
| SCHEMBL19839967 | 1.00 | ALOX15 (0.49) | ALOX15ALDH1A1GAATSHRNFKB1 | |
| SCHEMBL22697593 | 0.84 | TRPV1 (0.58) | ALOX15ALDH1A1GAATSHRTRPV1 | |
| SCHEMBL19839958 | 0.83 | TRPV1 (0.55) | ALDH1A1GAATSHRNFKB1TDP1 | |
| SCHEMBL17179832 | 0.82 | TSHR (0.58) | ALOX15ALDH1A1GAATSHRNFKB1 | |
| SCHEMBL30242334 | 0.82 | TSHR (0.58) | ALOX15ALDH1A1GAATSHRNFKB1 | |
| SCHEMBL17179822 | 0.80 | ALDH1A1 (0.58) | ALDH1A1GAATSHRNFKB1TDP1 | |
| SCHEMBL30242344 | 0.80 | ALDH1A1 (0.58) | ALDH1A1GAATSHRNFKB1TDP1 | |
| SCHEMBL874243 | 0.79 | ALOX15 (0.58) | ALOX15ALDH1A1TSHRTDP1TRPV1 | |
| SCHEMBL25061850 | 0.78 | ALDH1A1 (0.56) | ALOX15ALDH1A1GAATSHRNFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3494104-A1 | WARMING SENSATION COMPOUNDS | Takasago International Corporation (JP) | 2019-06-12 | — | — | EP | disclosed |
| WO-2018027202-A1 | WARMING SENSATION COMPOUNDS | TAKASAGO INTERNATIONAL CORPORATION (USA) (US) | 2018-02-08 | — | — | WO | disclosed |