Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | TRPV1 | Q8NER1 | 6/20 | 0.47 |
| ▸ | FOS | P01100 | 1/20 | 0.43 |
| ▸ | TTR | P02766 | 1/20 | 0.43 |
| ▸ | JUN | P05412 | 1/20 | 0.43 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.43 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.43 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.43 |
| ▸ | IARS1 | P41252 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21046217 | 1.00 | ALOX15 (0.49) | ALOX15ALDH1A1GAATSHRNFKB1 | |
| SCHEMBL19839960 | 1.00 | ALOX15 (0.49) | ALOX15ALDH1A1GAATSHRNFKB1 | |
| SCHEMBL22697593 | 0.84 | TRPV1 (0.58) | ALOX15ALDH1A1GAATSHRTRPV1 | |
| SCHEMBL19839958 | 0.83 | TRPV1 (0.55) | ALDH1A1GAATSHRNFKB1TDP1 | |
| SCHEMBL17179832 | 0.82 | TSHR (0.58) | ALOX15ALDH1A1GAATSHRNFKB1 | |
| SCHEMBL30242334 | 0.82 | TSHR (0.58) | ALOX15ALDH1A1GAATSHRNFKB1 | |
| SCHEMBL17179822 | 0.80 | ALDH1A1 (0.58) | ALDH1A1GAATSHRNFKB1TDP1 | |
| SCHEMBL30242344 | 0.80 | ALDH1A1 (0.58) | ALDH1A1GAATSHRNFKB1TDP1 | |
| SCHEMBL874243 | 0.79 | ALOX15 (0.58) | ALOX15ALDH1A1TSHRTDP1TRPV1 | |
| SCHEMBL25061850 | 0.78 | ALDH1A1 (0.56) | ALOX15ALDH1A1GAATSHRNFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3494104-B1 | WARMING SENSATION COMPOUNDS | TAKASAGO PERFUMERY CO LTD (JP) | 2023-11-15 | — | — | EP | disclosed |
| CN-109803948-B | Warming sensation compound | 高砂香料工业株式会社 | 2022-03-01 | — | — | CN | disclosed |
| US-11059771-B2 | Warming sensation compounds | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2021-07-13 | — | — | US | disclosed |
| US-11034644-B2 | — | — | 2021-06-15 | — | — | US | disclosed |
| EP-3494104-A1 | WARMING SENSATION COMPOUNDS | Takasago International Corporation (JP) | 2019-06-12 | — | — | EP | disclosed |
| US-20190169111-A1 | WARMING SENSATION COMPOUNDS | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2019-06-06 | — | — | US | disclosed |
| WO-2018027202-A1 | WARMING SENSATION COMPOUNDS | TAKASAGO INTERNATIONAL CORPORATION (USA) (US) | 2018-02-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11059771-B2 | Warming sensation compounds | TRPA1, TRPV1, TRPV4 | ALOX15 596/4885ALDH1A1 1286/4885GAA 1976/4885 |
| US-11034644-B2 | — | TRPA1, TRPV1, TRPV5 | ALOX15 326/4885ALDH1A1 593/4885GAA 704/4885 |
| US-20190169111-A1 | WARMING SENSATION COMPOUNDS | TRPA1, TRPV1, TRPV4 | ALOX15 596/4885ALDH1A1 1286/4885GAA 1976/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.