Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.36 |
| ▸ | HPGDS | O60760 | 4/20 | 0.35 |
| ▸ | CD274 | Q9NZQ7 | 7/20 | 0.34 |
| ▸ | PDCD1 | Q15116 | 5/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.33 |
| ▸ | RELA | Q04206 | 2/20 | 0.33 |
| ▸ | IDH1 | O75874 | 1/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19840984 | 0.88 | KMT2A (0.35) | HDAC1CD274PDCD1SMN1; SMN2NPC1 | |
| SCHEMBL19840811 | 0.85 | HPGDS (0.38) | HPGDSSMN1; SMN2NPC1RAB9AMEN1 | |
| SCHEMBL19841003 | 0.84 | SMN1; SMN2 (0.44) | HDAC1SMN1; SMN2MEN1KMT2ATDP1 | |
| SCHEMBL19840787 | 0.83 | MEN1 (0.47) | HDAC1SMN1; SMN2MEN1KMT2ATDP1 | |
| SCHEMBL19840905 | 0.82 | HPGDS (0.30) | HPGDS | |
| SCHEMBL19841130 | 0.82 | TSHR (0.34) | NPC1RAB9AMEN1KMT2ATDP1 | |
| SCHEMBL19840754 | 0.81 | CYP1A2 (0.31) | — | |
| SCHEMBL19840742 | 0.81 | — | — | |
| SCHEMBL19840959 | 0.79 | LOXL2 (0.39) | HDAC1CD274PDCD1 | |
| SCHEMBL19841088 | 0.79 | PDE10A (0.42) | HPGDS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9884832-B2 | Inhibitors targeting drug-resistant influenza A | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2018-02-06 | — | — | US | disclosed |