Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | UCHL1 | P09936 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.37 |
| ▸ | PTGES | O14684 | 2/20 | 0.36 |
| ▸ | SCN4A | P35499 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | PDE8B | O95263 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1984645 | 1.00 | ALDH1A1 (0.39) | ALDH1A1UCHL1KMT2ATSHRMEN1 | |
| SCHEMBL10173733 | 0.91 | ALDH1A1 (0.45) | ALDH1A1UCHL1KMT2ATSHRMEN1 | |
| SCHEMBL241258 | 0.91 | ALDH1A1 (0.45) | ALDH1A1UCHL1KMT2ATSHRMEN1 | |
| SCHEMBL241257 | 0.91 | ALDH1A1 (0.45) | ALDH1A1UCHL1KMT2ATSHRMEN1 | |
| SCHEMBL23247408 | 0.88 | ALDH1A1 (0.42) | ALDH1A1UCHL1KMT2ATSHRMEN1 | |
| SCHEMBL18058877 | 0.80 | ALDH1A1 (0.43) | ALDH1A1UCHL1KMT2ATSHRMEN1 | |
| SCHEMBL18731202 | 0.77 | UCHL1 (0.43) | ALDH1A1UCHL1KMT2ATSHRMEN1 | |
| SCHEMBL9936981 | 0.74 | HCRTR1 (0.38) | — | |
| SCHEMBL17396070 | 0.74 | ALDH1A1 (0.46) | ALDH1A1KMT2ATSHRMEN1L3MBTL1 | |
| SCHEMBL18291891 | 0.74 | ALDH1A1 (0.46) | ALDH1A1KMT2ATSHRMEN1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2337781-A2 | ANTI-VIRAL COMPOUNDS TO TREAT HCV INFECTION | Abbott Laboratories (US) | 2011-06-29 | — | — | EP | disclosed |
| WO-2010144646-A2 | ANTI-VIRAL COMPOUNDS | ABBOTT LABORATORIES (US) | 2010-12-16 | — | — | WO | disclosed |