SCHEMBL19847366

SCHEMBL19847366

Cc1cc(NC(=O)C(CC(C)(C)C)C(C)C)c(C)c(C)c1O

nearest known ligand 0.42

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
SOAT2 O75908 1/20 0.42
ACAT1 P24752 1/20 0.42
SOAT1 P35610 1/20 0.42
GAA P10253 2/20 0.34
THRA P10827 1/20 0.32
THRB P10828 1/20 0.32
PKM P14618 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24777446 0.76 SOAT2 (0.43) SOAT2ACAT1SOAT1
SCHEMBL8660749 0.75 SOAT2 (0.45) SOAT2ACAT1SOAT1GAATHRA
SCHEMBL21973919 0.73 POLB (0.32)
SCHEMBL25692946 0.70 ESR1 (0.34) GAATHRATHRB
SCHEMBL25631108 0.70 LMNA (0.51) SOAT2ACAT1SOAT1GAATHRB
SCHEMBL20345249 0.69 IDO1 (0.50) GAA
SCHEMBL9446304 0.69 SOAT2 (0.57) SOAT2ACAT1SOAT1GAA
SCHEMBL9446292 0.69 SOAT2 (0.57) SOAT2ACAT1SOAT1GAA
SCHEMBL19847377 0.69 CDC25B (0.45) GAA
SCHEMBL20403879 0.69 ALDH1A1 (0.50) PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3279734-B1 POSITIVE RESIST COMPOSITION, RESIST PATTERN FORMING PROCESS, AND PHOTOMASK BLANK SHINETSU CHEMICAL CO (JP) 2018-07-25 EP disclosed
EP-3343292-A1 CHEMICALLY AMPLIFIED NEGATIVE RESIST COMPOSITION AND RESIST PATTERN FORMING PROCESS Shin-Etsu Chemical Co., Ltd. (JP) 2018-07-04 EP disclosed
EP-3279734-A1 POSITIVE RESIST COMPOSITION, RESIST PATTERN FORMING PROCESS, AND PHOTOMASK BLANK Shin-Etsu Chemical Co., Ltd. (JP) 2018-02-07 EP disclosed