Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT2 | O75908 | 1/20 | 0.45 |
| ▸ | ACAT1 | P24752 | 1/20 | 0.45 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.45 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | THRB | P10828 | 2/20 | 0.34 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | THRA | P10827 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | LDHA | P00338 | 1/20 | 0.32 |
| ▸ | LDHB | P07195 | 1/20 | 0.32 |
| ▸ | TRPM4 | Q8TD43 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4969873 | 0.80 | GAA (0.43) | GPR35GAAMEN1KMT2AMAPT | |
| SCHEMBL19847366 | 0.75 | SOAT2 (0.42) | SOAT2ACAT1SOAT1GAATHRB | |
| SCHEMBL9446304 | 0.74 | SOAT2 (0.57) | SOAT2ACAT1SOAT1GAAMAPT | |
| SCHEMBL9446292 | 0.74 | SOAT2 (0.57) | SOAT2ACAT1SOAT1GAAMAPT | |
| SCHEMBL8043445 | 0.71 | SOAT2 (0.69) | SOAT2ACAT1SOAT1NPSR1LMNA | |
| SCHEMBL9575169 | 0.71 | TGM2 (0.47) | SOAT2ACAT1SOAT1LMNA | |
| SCHEMBL8079767 | 0.71 | LMNA (0.49) | SOAT2ACAT1SOAT1MEN1KMT2A | |
| SCHEMBL28622486 | 0.71 | IDO1 (0.36) | SOAT2ACAT1SOAT1GAAMEN1 | |
| SCHEMBL11731600 | 0.70 | NPC1 (0.60) | GAAMAPTLMNAPGRSCN1A | |
| SCHEMBL24777446 | 0.70 | SOAT2 (0.43) | SOAT2ACAT1SOAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0874812-A1 | NOVEL 2,3,5-TRIMETHYL-4-HYDROXY ANILIDE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTICAL USE THEREOF | PIERRE FABRE MEDICAMENT (FR) | 1998-11-04 | — | — | EP | disclosed |
| WO-1997019918-A1 | NOVEL 2,3,5-TRIMETHYL-4-HYDROXY ANILIDE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTICAL USE THEREOF | PIERRE FABRE MEDICAMENT (FR) | 1997-06-05 | — | — | WO | disclosed |