SCHEMBL19848848

SCHEMBL19848848

O=C1c2cccc(-n3c4ccccc4c4cc(-c5nc(-c6ccccc6)nc(-c6ccccc6)n5)ccc43)c2C(=O)N1c1ccccc1-c1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ NR1H2 P55055 1/20 0.43
▸ ALDH1A1 P00352 3/20 0.41
▸ POLB P06746 1/20 0.40
▸ HTT P42858 1/20 0.40
▸ HSD17B10 Q99714 1/20 0.40
▸ TYMS P04818 1/20 0.40
▸ MGLL Q99685 1/20 0.36
▸ PDE6D O43924 1/20 0.36
▸ LMNA P02545 2/20 0.34
▸ MEN1 O00255 1/20 0.34
▸ HPGD P15428 1/20 0.34
▸ KMT2A Q03164 1/20 0.34
▸ PLAUR Q03405 1/20 0.34
▸ ENPP2 Q13822 1/20 0.32
▸ MAPK14 Q16539 1/20 0.32
▸ CASP3 P42574 1/20 0.32
▸ PDCD1 Q15116 1/20 0.32
▸ CD274 Q9NZQ7 1/20 0.32
▸ HSPA1A P0DMV8 1/20 0.32
▸ PABPC1 P11940 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19848810 0.97 NR1H2 (0.45) NR1H2ALDH1A1POLBHTTHSD17B10
SCHEMBL19850268 0.95 TYMS (0.43) NR1H2ALDH1A1POLBHTTHSD17B10
SCHEMBL19843526 0.94 TYMS (0.40) NR1H2ALDH1A1POLBHTTHSD17B10
SCHEMBL19843492 0.94 POLB (0.39) NR1H2ALDH1A1POLBHTTHSD17B10
SCHEMBL19843479 0.94 NR1H2 (0.43) NR1H2ALDH1A1POLBHTTHSD17B10
SCHEMBL19843438 0.93 TYMS (0.38) NR1H2ALDH1A1POLBHTTHSD17B10
SCHEMBL19843024 0.92 TYMS (0.42) NR1H2ALDH1A1POLBHTTHSD17B10
SCHEMBL23476443 0.92 TYMS (0.45) NR1H2ALDH1A1POLBHTTHSD17B10
SCHEMBL23516108 0.92 HSPA1A (0.41) ALDH1A1POLBHTTTYMSPDE6D
SCHEMBL23516293 0.91 PDE6D (0.45) ALDH1A1POLBHTTTYMSPDE6D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12029120-B2 Organic electroluminescence element and electronic device IDEMITSU KOSAN CO., LTD. (JP) 2024-07-02 — — US disclosed
US-20230301188-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, ORGANIC ELECTROLUMINESCENT LIGHT-EMITTING DEVICE, AND ELECTRONIC EQUIPMENT IDEMITSU KOSAN CO., LTD. (JP) 2023-09-21 — — US disclosed
US-20230301188-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, ORGANIC ELECTROLUMINESCENT LIGHT-EMITTING DEVICE, AND ELECTRONIC EQUIPMENT IDEMITSU KOSAN CO., LTD. (JP) 2023-09-21 — — US disclosed
US-20220380387-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC APPLIANCE IDEMITSU KOSAN CO.,LTD. (JP) 2022-12-01 — — US disclosed
US-11380850-B2 Organic electroluminescent devices comprising host compounds CYNORA GMBH (DE) 2022-07-05 — — US disclosed
US-11276825-B2 Organic molecules for use in organic devices CYNORA GMBH (DE) 2022-03-15 — — US disclosed
US-20210184134-A1 ORGANIC MOLECULES FOR USE IN ORGANIC DEVICES SAMSUNG DISPLAY CO., LTD. (KR) 2021-06-17 — — US disclosed
US-20210171501-A1 ORGANIC MOLECULES FOR USE IN ORGANIC OPTOELECTRONIC DEVICES SAMSUNG DISPLAY CO., LTD. (KR) 2021-06-10 — — US disclosed
US-20190259958-A1 ORGANIC ELECTROLUMINESCENT DEVICES COMPRISING HOST COMPOUNDS SAMSUNG DISPLAY CO., LTD. (KR) 2019-08-22 — — US disclosed
EP-3279193-B1 COMPOUNDS COMPRISING A PHTHALIMIDE GROUP AND CARBAZOLE OR ITS ANALOGUES FOR USE IN ORGANIC OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2019-05-08 — — EP disclosed
US-9917270-B1 Organic electroluminescent device having an exciton quenching layer CYNORA GMBH (DE) 2018-03-13 — — US disclosed
US-9917270-B1 Organic electroluminescent device having an exciton quenching layer CYNORA GMBH (DE) 2018-03-13 — — US disclosed
WO-2018024723-A1 PHTHALIMIDE AND CARBAZOLE OR ANALOGS THEREOF CONTAINING COMPOUNDS FOR USE IN ORGANIC OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2018-02-08 — — WO disclosed
EP-3279193-A1 COMPOUNDS COMPRISING PHTHALIMIDE AND CARBAZOLE OR ITS ANALOGUES FOR USE IN ORGANIC OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2018-02-07 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230301188-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, ORGANIC ELECTROLUMINESCENT LIGHT-EMITTING DEVICE, AND ELECTRONIC EQUIPMENT EED, LEF1, EML4 NR1H2 857/4885ALDH1A1 468/4885POLB 922/4885
US-20210171501-A1 ORGANIC MOLECULES FOR USE IN ORGANIC OPTOELECTRONIC DEVICES L1CAM, OR10J3, AOX1 NR1H2 2382/4885ALDH1A1 20/4885POLB 1988/4885
US-12029120-B2 Organic electroluminescence element and electronic device RPS10, H1-10, OR10J3 NR1H2 2006/4885ALDH1A1 374/4885POLB 1478/4885
US-20210184134-A1 ORGANIC MOLECULES FOR USE IN ORGANIC DEVICES CHRM1, C1S, DNMT3L NR1H2 270/4885ALDH1A1 930/4885POLB 726/4885
US-20220380387-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC APPLIANCE H1-2, H1-0, CCNE2 NR1H2 1625/4885ALDH1A1 1796/4885POLB 1618/4885
US-11276825-B2 Organic molecules for use in organic devices AOX1, OR10J3, L1CAM NR1H2 595/4885ALDH1A1 11/4885POLB 733/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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