SCHEMBL19851267

SCHEMBL19851267

C=CC(F)(F)c1ccc(Br)nc1

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21436992 0.82 KMT2A (0.34) KMT2A
SCHEMBL67213 0.77 KMT2A (0.47) KMT2A
SCHEMBL19851266 0.77 KMT2A (0.30) KMT2A
SCHEMBL31507733 0.76 NR1H2 (0.34)
SCHEMBL1554553 0.74 MBOAT4 (0.33) KMT2A
SCHEMBL28017609 0.74 L3MBTL1 (0.33) KMT2A
SCHEMBL7644558 0.73 NR1H2 (0.34)
SCHEMBL24258401 0.73 DAO (0.32) KMT2A
SCHEMBL23536244 0.73 CA1 (0.42)
SCHEMBL29080924 0.72 FDFT1 (0.33) KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018024653-A1 OXADIAZOLOPYRIDINE DERIVATES FOR USE AS GHRELIN O-ACYL TRANSFERASE (GOAT) INHIBITORS BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2018-02-08 WO disclosed