SCHEMBL1985142

SCHEMBL1985142

O=C1c2ccccc2Cc2c(Br)c(Br)c3ccccc3c21

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 2/20 0.48
CES1 P23141 2/20 0.46
BCHE P06276 1/20 0.46
ALDH1A1 P00352 5/20 0.40
CYP1A2 P05177 1/20 0.40
CYP2C19 P33261 1/20 0.40
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
CA4 P22748 1/20 0.39
CA6 P23280 1/20 0.39
MAP3K9 P80192 5/20 0.39
MAP3K11 Q16584 5/20 0.39
MAPT P10636 2/20 0.38
KDM4E B2RXH2 2/20 0.38
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
POLB P06746 1/20 0.38
HPGD P15428 1/20 0.38
NPC1 O15118 1/20 0.38
RAB9A P51151 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL260885 0.83 MAOA (0.55) MAOACES1BCHEALDH1A1CYP1A2
SCHEMBL10944994 0.81 MAOA (0.53) MAOACES1BCHEALDH1A1CYP1A2
SCHEMBL9811799 0.77 MAOA (0.48) MAOACES1BCHEALDH1A1CYP1A2
SCHEMBL1987356 0.74 MAOA (0.53) MAOACES1BCHEALDH1A1CYP1A2
SCHEMBL9356907 0.74 CES1 (0.46) MAOACES1BCHEALDH1A1CYP1A2
SCHEMBL8622497 0.73 MAP3K9 (0.42) MAOACES1BCHEALDH1A1CA1
SCHEMBL10703055 0.71 MAOA (0.59) MAOACES1BCHEALDH1A1CYP1A2
SCHEMBL11505033 0.71 MAOA (0.44) MAOACES1BCHEALDH1A1CYP1A2
SCHEMBL11145048 0.71 MAOA (0.44) MAOACES1BCHEALDH1A1CYP1A2
SCHEMBL525516 0.70 MAOA (0.57) MAOACES1BCHEALDH1A1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2085431-B1 Benzothioxanthene dyes with improved application and toxicological properties CLARIANT FINANCE BVI LTD (VG) 2011-06-29 EP claimed
US-20090255440-A1 Benzothioxanthene dyes with improved application and toxicological properties CLARIANT INTERNATIONAL LTD. 2009-10-15 US claimed
EP-2085431-A1 Benzothioxanthene dyes with improved application and toxicological properties CLARIANT INTERNATIONAL LTD. (CH) 2009-08-05 EP claimed
US-5736285-A PHOTOSENSITIVE LAYER CONTAINS CHARGE TRANSPORTING POLYESTER AND ATLEAST ONE BISAZO PIGMENT; WEAR RESISTANCE AND ELECTRIC STABILITY FUJI XEROX CO., LTD. (JP) 1998-04-07 US claimed
EP-0136981-B1 PROCESS FOR THE PREPARATION OF ANTHRAQUINONE IMIDE COMPOUNDS CIBA-GEIGY AG (CH) 1989-04-05 EP claimed
US-4659831-A Process for the preparation of anthraquinone imides CIBA-GEIGY AG (CH) 1987-04-21 US claimed
JP-8085764-A None JP disclosed
EP-2085431-B1 Benzothioxanthene dyes with improved application and toxicological properties CLARIANT FINANCE BVI LTD (VG) 2011-06-29 EP disclosed
US-7790057-B2 Electroluminescent polymers and use thereof MERCK PATENT GMBH (DE) 2010-09-07 US disclosed
US-20090318625-A1 ELECTROLUMINESCENT POLYMERS AND USE THEREOF MERCK PATENTS GMBH PATENTS & SCIENTIFIC INFORMATION (DE) 2009-12-24 US disclosed
US-20090255440-A1 Benzothioxanthene dyes with improved application and toxicological properties CLARIANT INTERNATIONAL LTD. 2009-10-15 US disclosed
EP-2085431-A1 Benzothioxanthene dyes with improved application and toxicological properties CLARIANT INTERNATIONAL LTD. (CH) 2009-08-05 EP disclosed
US-5736285-A PHOTOSENSITIVE LAYER CONTAINS CHARGE TRANSPORTING POLYESTER AND ATLEAST ONE BISAZO PIGMENT; WEAR RESISTANCE AND ELECTRIC STABILITY FUJI XEROX CO., LTD. (JP) 1998-04-07 US disclosed
JP-H0885764-A PURIFICATION OF DIBROMOBENZANTHRONE MITSUI TOATSU CHEM INC 1996-04-02 JP disclosed
US-4659831-A Process for the preparation of anthraquinone imides CIBA-GEIGY AG (CH) 1987-04-21 US disclosed
US-4146547-A Manufacture of Bz-1-bromobenzanthrone BASF AKTIENGESELLSCHAFT (DE) 1979-03-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090318625-A1 ELECTROLUMINESCENT POLYMERS AND USE THEREOF EPN1, MAP1LC3C, MAP1LC3A MAOA 564/4885CES1 2304/4885BCHE 4269/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.