Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC15A1 | P46059 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CTSS | P25774 | 1/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.37 |
| ▸ | CDC25B | P30305 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18265983 | 0.81 | ALDH1A1 (0.51) | SLC15A1ALDH1A1MAPK1L3MBTL1CTSS | |
| SCHEMBL19852383 | 0.79 | CTSS (0.42) | ALDH1A1MAPK1L3MBTL1CTSSAAK1 | |
| SCHEMBL7705289 | 0.79 | ALDH1A1 (0.54) | SLC15A1ALDH1A1MAPK1L3MBTL1ABCB1 | |
| SCHEMBL19852397 | 0.79 | SLC15A1 (0.46) | SLC15A1ALDH1A1MAPK1L3MBTL1CTSS | |
| SCHEMBL18914889 | 0.76 | ALDH1A1 (0.50) | SLC15A1ALDH1A1MAPK1L3MBTL1ABCB1 | |
| SCHEMBL111390 | 0.75 | ALDH1A1 (0.61) | SLC15A1ALDH1A1MAPK1L3MBTL1ABCB1 | |
| Hydrochloric Acid SCHEMBL28176642 | 0.74 | ALDH1A1 (0.59) | SLC15A1ALDH1A1MAPK1L3MBTL1ABCB1 | |
| SCHEMBL27674121 | 0.74 | ALDH1A1 (0.59) | SLC15A1ALDH1A1MAPK1L3MBTL1ABCB1 | |
| SCHEMBL23843034 | 0.73 | ALDH1A1 (0.50) | SLC15A1ALDH1A1MAPK1L3MBTL1POLB | |
| SCHEMBL18207072 | 0.73 | ALDH1A1 (0.50) | SLC15A1ALDH1A1MAPK1L3MBTL1ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10640725-B2 | Thermocleavable friction modifiers and methods thereof | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2020-05-05 | — | — | US | disclosed |
| US-20180037840-A1 | THERMOCLEAVABLE FRICTION MODIFIERS AND METHODS THEREOF | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2018-02-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180037840-A1 | THERMOCLEAVABLE FRICTION MODIFIERS AND METHODS THEREOF | F12, F5, F3 | SLC15A1 4229/4885ALDH1A1 3303/4885MAPK1 1749/4885 |
| US-10640725-B2 | Thermocleavable friction modifiers and methods thereof | F12, F5, F3 | SLC15A1 4229/4885ALDH1A1 3303/4885MAPK1 1749/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.