Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | KDM5A | P29375 | 2/20 | 0.34 |
| ▸ | KDM4A | O75164 | 11/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 11/20 | 0.33 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.33 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.33 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.33 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30185810 | 1.00 | ALDH1A1 (0.55) | ALDH1A1TSHRLMNAKDM5AKDM4A | |
| SCHEMBL499415 | 0.98 | ALDH1A1 (0.52) | ALDH1A1TSHRLMNAKDM5AKDM4A | |
| SCHEMBL4766606 | 0.92 | ALDH1A1 (0.43) | ALDH1A1TSHRLMNAKDM5A | |
| SCHEMBL29991123 | 0.89 | ALDH1A1 (0.41) | ALDH1A1LMNAKDM5AKDM4AKDM4C | |
| SCHEMBL24703880 | 0.87 | ALDH1A1 (0.42) | ALDH1A1TSHRLMNAKDM5AKDM4A | |
| SCHEMBL17520374 | 0.83 | ALDH1A1 (0.59) | ALDH1A1TSHRLMNAKDM5AKDM4A | |
| SCHEMBL5117460 | 0.83 | ALDH1A1 (0.37) | ALDH1A1TSHRLMNA | |
| SCHEMBL22205611 | 0.83 | LMNA (0.44) | ALDH1A1TSHRLMNAKDM5AKDM4A | |
| SCHEMBL29053198 | 0.82 | CHRNB2 (0.40) | ALDH1A1TSHRLMNAKDM5AKDM4A | |
| SCHEMBL28447170 | 0.82 | CHRNB2 (0.40) | ALDH1A1TSHRLMNAKDM5AKDM4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018026371-A1 | DUAL NAV1.2/5HT2A INHIBITORS FOR TREATING CNS DISORDERS | SUNOVION PHARMACEUTICALS INC. (US) | 2018-02-08 | — | — | WO | disclosed |